Results 21 to 30 of about 1,233,920 (254)

A simple and fast method to image calcium activity of neurons from intact dorsal root ganglia using fluorescent chemical Ca indicators

Molecular Pain, 2017
Chemical calcium indicators have been commonly used to monitor calcium (Ca 2+ ) activity in cell bodies, i.e., somata, of isolated dorsal root ganglion neurons.
Yong Chen, Li-Yen M Huang
doaj   +1 more source

NEURAL PAIN PATHWAY TRACING OF RABBIT ISCHEMIC HEART BY DOUBLE-RETROGRADE NEUROTRACING

Malang Neurology Journal, 2015
Background. Myocardial ischaemia occurs due to inadequate supply of oxygen to fulfill the myocardial tissue oxygen demand. This leads to angina pectoris or referred pain, whichhappens because of the inability of the brain to distinguish the visceral ...
Theodorus Dapamede, Obed Trinurcahyo Kinantyo Paundralingga, Masruroh Rahayu, Bambang Soemantri   +3 more
doaj   +1 more source

Regulation of boundary cap neural crest stem cell differentiation after transplantation [PDF]

, 2009
Success of cell replacement therapies for neurological disorders will depend largely on the optimization of strategies to enhance viability and control the developmental fate of stem cells after transplantation.
Hjerling-Leffler, J, Aldskogius, Hakan, Wegner, M, Hjerling-Leffler, Jens, Kozlova, Elena N, Medvinsky, Alexander, Berens, C, Aldskogius, H, Kozlova, EN, Berens, Christian, Kanaykina, Nadezda, Sandelin, Martin, Schreiner, S, Wegner, Michael, Kanaykina, N, Sandelin, M, Liakhovitskaia, A, Medvinsky, A, Liakhovitskaia, Anna, Schreiner, Silke   +19 more
core   +1 more source

Fatty-acid-binding protein inhibition produces analgesic effects through peripheral and central mechanisms

Molecular Pain, 2017
Background Fatty-acid-binding proteins (FABPs) are intracellular carriers for endocannabinoids, N-acylethanolamines, and related lipids. Previous work indicates that systemically administered FABP5 inhibitors produce analgesia in models of inflammatory ...
Xiaoxue Peng, Keith Studholme, Martha P Kanjiya, Jennifer Luk, Diane Bogdan, Matthew W Elmes, Gregory Carbonetti, Simon Tong, Yu-Han Gary Teng, Robert C Rizzo, Huilin Li, Dale G Deutsch, Iwao Ojima, Mario J Rebecchi, Michelino Puopolo, Martin Kaczocha   +15 more
doaj   +1 more source

A Subset of Oligodendrocyte Lineage Cells Interact With the Developing Dorsal Root Entry Zone During Its Genesis

Frontiers in Cellular Neuroscience, 2022
Oligodendrocytes are the myelinating cell of the CNS and are critical for the functionality of the nervous system. In the packed CNS, we know distinct profiles of oligodendrocytes are present.
Lauren A. Green, Lauren A. Green, Robert M. Gallant, Jacob P. Brandt, Ev L. Nichols, Cody J. Smith, Cody J. Smith   +6 more
doaj   +1 more source

Developmental changes in voltage-gated calcium channel α(2)δ-subunit expression in the canine dorsal root ganglion [PDF]

, 2012
The voltage-gated calcium channel subunit (128 plays a fundamental role in propagation of excitatory signals associated with release of glutamate and neuropeptides substance P (SP) and calcitonin gene-related protein (CGRP).
K. Matiasek, Matiasek, K, Gualtiereo, G, Goedde, Th, F. Steffen, Reese, S, Rosati, M, T. Goedde, Steffen, Frank, Goedde, Thomas, Steffen, F, S. Reese, Rosati, Marco, Reese, Sven, De Risio, Luisa, Matiasek, Kaspar, L. De Risio, DeRisio, L, Gandini, Gualtiero   +18 more
core   +1 more source

Avaliação da hiperalgesia e alterações histológicas do gânglio da raiz dorsal induzidas pelo núcleo pulposo Evaluation of hyperalgesia and histological changes of dorsal root ganglion induced by nucleus pulposus

Revista Brasileira de Ortopedia, 2010
OBJETIVO: Avaliar a hiperalgesia e as alterações histológicas induzidas pelo contato do gânglio da raiz dorsal com o núcleo pulposo. MÉTODOS: Foram utilizados 20 ratos Wistar, divididos em dois grupos experimentais.
André Luiz de Souza Grava, Luiz Fernando Ferrari, Carlos Amílcar Parada, Helton Luiz Aparecido Defino   +3 more
doaj   +1 more source

Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito, Kamal Benguerba, Ken Tsuchida, Kazushige Yazawa, Isao Tsumiyama, Hiromitsu Kayama, Sandra P. Reyna, Farid Khan, Richard S. Finkel   +8 more
wiley   +1 more source

Single-cell RNA sequencing of the post–spinal cord injury dorsal root ganglia in cynomolgus monkeys: Elucidation of the cellular immune microenvironment of the central nervous system

Neural Regeneration Research
Few studies have investigated alterations in the immune cell microenvironment of the dorsal root ganglia following spinal cord injury and whether these modifications facilitate axonal regeneration.
Yiming Ren, Bo Li, Bo Yang, Baoyou Fan, Shenghui Huang, Guidong Shi, Liang Liu, Zhijian Wei, Shiqing Feng   +8 more
doaj   +1 more source

Neuromedin B Induces Acute Itch in Mice via the Activation of Peripheral Sensory Neurons

Acta Dermato-Venereologica, 2019
Neuromedin B is expressed in nociceptive and itch-sensitive dorsal root ganglia neurons, but its peripheral pruritogenic potential is not well described. The potential of neuromedin B as a pruritogen and pro-inflammatory peptide in the skin was tested in
Sarah Ehling, Tomoki Fukuyama, Mei-Chuan Ko, Thierry Olivry, Wolfgang Bäumer   +4 more
doaj   +1 more source