Results 141 to 150 of about 110,913 (229)

Mathematics anxiety: Effects of age, gender and culture

British Journal of Educational Psychology, Volume 96, Issue 2, Page 896-921, June 2026.
Abstract Background Many studies have indicated that mathematics anxiety is a significant problem for many people and is an important topic for research. Mathematics anxiety is multidimensional. In particular, it is important to distinguish between worry and emotionality components, and between trait and state anxiety.
Ann Dowker
wiley   +1 more source

Identification of Alzheimer's disease subtypes and biomarkers from human multi‐omics data using subspace merging algorithm

Alzheimer's &Dementia, Volume 22, Issue 5, May 2026.
Abstract INTRODUCTION Alzheimer's disease (AD) is a heterogeneous disease with diverse disease progression trajectories and brain pathology. Identifying AD subtypes is essential for understanding AD etiology, heterogeneity, and developing precise treatment. METHODS We applied a subspace‐merging algorithm to integrate multi‐omics data from brain tissues
Ziyan Song, Xiaoqing Huang, Asha Jacob Jannu, Travis S. Johnson, Jie Zhang, Kun Huang   +5 more
wiley   +1 more source

Selective reduction of KCNA4 in vulnerable glutamatergic–serotonin neurons of the dorsal raphe nucleus in Alzheimer's disease

Alzheimer's &Dementia, Volume 22, Issue 5, May 2026.
Abstract INTRODUCTION Our previous studies demonstrate that htau mice recapitulate many of the neuropsychiatric features of early Alzheimer's disease (AD), and that the dorsal raphe nucleus (DRN) contains distinct subregions. Herein, we investigate the vulnerability of the centromedial DRN to pathologically phosphorylated tau (p‐tau), a region composed
Louis J. Kolling, Nagalakshmi Balasubramanian, Shafa Ismail, Alexander J. Feller, Jessica Marie Hunter Alberhasky, Ruixiang Wang, Luke Jennings, Marco Hefti, Catherine Anne Marcinkiewcz   +8 more
wiley   +1 more source

circPDE4B downregulation triggers GEMIN5‑dependent translational stress response and autophagy to reduce MAPT pathology

Alzheimer's &Dementia, Volume 22, Issue 5, May 2026.
Abstract INTRODUCTION Circular RNAs (circRNAs) are emerging as key regulators of gene expression, synaptic plasticity, and neuronal function in Alzheimer's disease (AD). Here, we characterize the biological actions of circPDE4B, a highly expressed circRNA markedly reduced in AD. METHODS circPDE4B knockdown in neuronal progenitor cells was combined with
Sambhavi Puri, Sophie J. F. van der Spek, Mintao Lin, Zihan Wang, Jacob Porter, Junming Hu, Liyuan Hu, Alejandro N. Rondón‐Ortiz, Alexander Knyshov, Jenna L. Libera, Scott E. Counts, Debomoy K. Lahiri, Julia TCW, Andrew Emili, Xiaoling Zhang, Benjamin Wolozin   +15 more
wiley   +1 more source

Multimodal MRI Reveals Brain Structural Differences and Executive Dysfunction in Early Methamphetamine Abstinence

Brain and Behavior, Volume 16, Issue 5, May 2026.
In a sample of 13 early‐abstinent methamphetamine users (≤30 days) and 14 controls, multimodal MRI revealed lower cortical volume in frontal and lingual regions and thickness of the lateral occipital and lingual cortex. These structural changes accompanied poorer executive performance, suggesting dose‐related grey‐matter vulnerability in visual ...
Ben Bristow, Maryam Tayebi, Paul Condron, Taylor Emsden, Tutarangi Ngarima, Eryn Kwon, Rachael McLanachan, Gordon Liu, William Schierding, Patrick McHugh, Samantha Holdsworth, Wendy Mohi, Gil Newburn, Miriam Scadeng   +13 more
wiley   +1 more source

The dorsolateral prefrontal cortex as a potential target for electrical stimulation in the treatment of vestibular-based nausea. [PDF]

J Physiol
McCarthy B, Howden EJ, Macefield VG.
europepmc   +1 more source

Regional Brain Activity Alterations in Social Anxiety Disorder Revealed by Seed‐Based d Mapping With Permutation of Subject Images

Brain and Behavior, Volume 16, Issue 5, May 2026.
This SDM‐PSI meta‐analysis identified consistent regional brain activity alterations in social anxiety disorder, including hyperactivity in the left superior parietal gyrus, right cerebellum, and right supramarginal gyrus, and hypoactivity in the left insula and right supplementary motor area, with age and symptom severity modulating specific regions ...
Sen Li, Ziqi Zhang, Shanling Ji, Aoxue Zhang, Shengbo Han, Zhengyang Chang, Kun Li, Jian Cui, Hao Yu, Chuanxin Liu, Cong Zhou   +10 more
wiley   +1 more source

Analysis of NDNF and SLC1A2 gene expression in the dorsolateral prefrontal cortex of individuals with autism. [PDF]

Front Neurosci
de Andrade AM, de Souza LRV, Oliveira RF, Paiva KM, Fiuza FP, de Farias PHS, da Silva Júnior RR, Holanda MVF, de Medeiros Fernandes TAA, de Góis Morais PLA, de Paiva Cavalcanti JRL.   +10 more
europepmc   +1 more source

Sustained Attention Instability as a Cognitive Biomarker in Chronic Spine Pain: A 90‐second Visual Attention Test

European Journal of Pain, Volume 30, Issue 5, May 2026.
ABSTRACT Background Chronic spine pain is linked to self‐reported cognitive complaints. However, objective markers are lacking. The 90‐s Continuous Visual Attention Test (CVAT) quantifies key attention subdomains: reaction time (RT, alertness), RT variability (VRT, sustained attention), omission errors (focused attention) and commission errors ...
Kai‐Uwe Lewandrowski, Kenneth Blum, Morgan Lorio, Colin Hanna, Alexander P. L. Lewandrowski, Thomas Lundquist, Rossano Kepler Alvim Fiorelli, Guilherme J. Schmidt, Emmanouil Liodakis, Mark Gold, Juliana J. Schmidt, Eelco Van Duinkerken, Carolina Abramovicz, Andreza P. Maia, Sergio Luis Schmidt   +14 more
wiley   +1 more source

Uncovering the signatures of aging and senescence in the human dorsolateral prefrontal cortex. [PDF]

Cell Genom
Sloan NX, Mares J, Daly AC, Grier S, Haq I, Jackson CA, Barretto N, Casel O, Kang K, Khiste S, Harris K, Eschbach J, Fullerton BT, Mattison C, Gebremedhin B, Petrescu J, Coie L, Pedersen MH, Zhang K, Shu J, Teich AF, Reddy H, Smith CP, Suh Y, Menon V, Phatnani H.   +25 more
europepmc   +1 more source