Results 151 to 160 of about 110,913 (229)

Next Generation 7 Tesla Arterial Spin Labeling With Rotated Spiral Acquisition Enables Mesoscale Resolution in 3D Brain Perfusion and Functional MRI

open access: yesMagnetic Resonance in Medicine, Volume 95, Issue 5, Page 2702-2717, May 2026.
ABSTRACT Purpose To achieve high resolution (≤ 1 mm isotropic) whole‐brain perfusion imaging at 7 T with next generation ASL pulse sequence, reconstruction algorithm, and MRI hardware. Methods We capitalized on three major innovations: (1) FLASH‐based pseudo‐Continuous ASL (pCASL) sequence with rotated golden‐angle stack‐of‐spirals (rGA‐SoS) sampling; (
Chenyang Zhao   +8 more
wiley   +1 more source

GatorST: A Versatile Contrastive Meta‐Learning Framework for Spatial Transcriptomic Data Analysis

open access: yesSmall Methods, Volume 10, Issue 9, 8 May 2026.
GatorST learns spatially informed embeddings for spatial transcriptomics by coupling two‐hop subgraph graph convolutions with cluster‐aware pseudo‐label supervision and episodic contrastive meta‐learning. The framework captures neighbor‐level topology and tissue‐wide expression semantics without heavy augmentations, delivering robust representations ...
Zhenhao Zhang   +5 more
wiley   +1 more source

Multi‐Omics Reveals Dysregulated Neurotransmitter Systems in Aging and CNS Disorders

open access: yesAging Cell, Volume 25, Issue 5, May 2026.
Integrating large‐scale human snRNA‐seq, spatial transcriptomics, and cerebral organoid datasets reveals cell‐type‐specific neurotransmitter‐system remodeling across aging and CNS disorders. Shared and disease‐specific NTS alterations highlight candidate mechanisms, sex differences, and exploratory discriminatory signals that may guide mechanistic ...
Rui‐Ze Niu   +11 more
wiley   +1 more source

Functional properties of dorsolateral prefrontal cortex to primary motor cortex connectivity: a dual-site TMS study. [PDF]

open access: yesFront Hum Neurosci
Lin XM   +9 more
europepmc   +1 more source

Pharmacological and Mechanistic Interventions for Cognitive Impairment Associated With Schizophrenia: A Review of Registered Clinical Trials

open access: yesActa Psychiatrica Scandinavica, Volume 153, Issue 5, Page 402-431, May 2026.
ABSTRACT Background Schizophrenia is characterized by positive, negative, and cognitive symptoms. Current pharmacological treatments often fail to address cognitive deficits. In this review of clinical trials, we aim to identify studies that explore neurobiological (non‐psychological) strategies to address Cognitive Impairment Associated with ...
Bahareh Peyrovian   +3 more
wiley   +1 more source

rTMS Suppresses Tobacco Craving via Enhanced Prefronto‐Striato‐Thalamic Connectivity

open access: yesAddiction Biology, Volume 31, Issue 5, May 2026.
This study aimed to investigate the therapeutic effects of rTMS on tobacco use disorder (TUD). The findings demonstrated that participants with TUD exhibited reduced cigarette cravings following treatment, accompanied by a reorganization of the prefrontal–striatal pathway and enhanced top‐down cognitive control.
Xin Luo   +6 more
wiley   +1 more source

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