ABSTRACT Purpose To achieve high resolution (≤ 1 mm isotropic) whole‐brain perfusion imaging at 7 T with next generation ASL pulse sequence, reconstruction algorithm, and MRI hardware. Methods We capitalized on three major innovations: (1) FLASH‐based pseudo‐Continuous ASL (pCASL) sequence with rotated golden‐angle stack‐of‐spirals (rGA‐SoS) sampling; (
Chenyang Zhao +8 more
wiley +1 more source
Transcranial direct current stimulation of the dorsolateral prefrontal cortex improves dual-task performance in people with stroke. [PDF]
Li S, Chen P, Qin Y, Wong TWL, Ng SSM.
europepmc +1 more source
GatorST: A Versatile Contrastive Meta‐Learning Framework for Spatial Transcriptomic Data Analysis
GatorST learns spatially informed embeddings for spatial transcriptomics by coupling two‐hop subgraph graph convolutions with cluster‐aware pseudo‐label supervision and episodic contrastive meta‐learning. The framework captures neighbor‐level topology and tissue‐wide expression semantics without heavy augmentations, delivering robust representations ...
Zhenhao Zhang +5 more
wiley +1 more source
Aberrant MicroRNA-124 expression and methylation in the dorsolateral prefrontal cortex of depressed subjects. [PDF]
Funahashi Y, Ochi S, Roy B, Dwivedi Y.
europepmc +1 more source
Multi‐Omics Reveals Dysregulated Neurotransmitter Systems in Aging and CNS Disorders
Integrating large‐scale human snRNA‐seq, spatial transcriptomics, and cerebral organoid datasets reveals cell‐type‐specific neurotransmitter‐system remodeling across aging and CNS disorders. Shared and disease‐specific NTS alterations highlight candidate mechanisms, sex differences, and exploratory discriminatory signals that may guide mechanistic ...
Rui‐Ze Niu +11 more
wiley +1 more source
Functional properties of dorsolateral prefrontal cortex to primary motor cortex connectivity: a dual-site TMS study. [PDF]
Lin XM +9 more
europepmc +1 more source
ABSTRACT Background Schizophrenia is characterized by positive, negative, and cognitive symptoms. Current pharmacological treatments often fail to address cognitive deficits. In this review of clinical trials, we aim to identify studies that explore neurobiological (non‐psychological) strategies to address Cognitive Impairment Associated with ...
Bahareh Peyrovian +3 more
wiley +1 more source
Efficacy of 5-Hz Transcranial Magnetic Stimulation Over the Left Dorsolateral Prefrontal Cortex in Improving Cognitive Function During the Recovery Phase of Stroke. [PDF]
Yu HX, Diao Q, Han YJ, Wei B, Dai P.
europepmc +1 more source
rTMS Suppresses Tobacco Craving via Enhanced Prefronto‐Striato‐Thalamic Connectivity
This study aimed to investigate the therapeutic effects of rTMS on tobacco use disorder (TUD). The findings demonstrated that participants with TUD exhibited reduced cigarette cravings following treatment, accompanied by a reorganization of the prefrontal–striatal pathway and enhanced top‐down cognitive control.
Xin Luo +6 more
wiley +1 more source
Stimulation of the right dorsolateral prefrontal cortex reduces conflict-induced forgetting. [PDF]
Kovacs O +4 more
europepmc +1 more source

