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The role of the dorsolateral prefrontal cortex in the inhibition of stereotyped responses
Experimental Brain Research, 2010Stereotyped behaviors should be inhibited under some circumstances in order to encourage appropriate behavior. Psychiatrists have used the modified rock-paper-scissors (RPS) task to examine the inhibition of stereotyped behavior. When subjects are required to lose in response to a gesture, it is difficult for them to lose, and they have a tendency to ...
Hiroshi, Kadota +5 more
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Neural correlates of a decision in the dorsolateral prefrontal cortex of the macaque
Nature Neuroscience, 1999To make a visual discrimination, the brain must extract relevant information from the retina, represent appropriate variables in the visual cortex and read out this representation to decide which of two or more alternatives is more likely. We recorded from neurons in the dorsolateral prefrontal cortex (areas 8 and 46) of the rhesus monkey while it ...
J N, Kim, M N, Shadlen
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Upregulation of cornichon transcripts in the dorsolateral prefrontal cortex in schizophrenia
NeuroReport, 2012Schizophrenia has been proposed to be associated with abnormal glutamatergic neurotransmission. The AMPA subtype of glutamate receptors (AMPARs) mediates fast excitatory synaptic transmission in the brain, and their trafficking and function is regulated in part by AMPAR auxiliary proteins including the cornichons (CNIH) and transmembrane AMPAR ...
Jana B, Drummond +3 more
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The role of the dorsolateral prefrontal cortex in the motor placebo effect
European Journal of Neuroscience, 2018AbstractThe neural correlates of the placebo effect in the motor domain are still unknown. The aim of this study was to tackle the role of a frontal cortical region, the dorsolateral prefrontal cortex (dlPFC). To this end, we stimulated the cortical site corresponding to the left dlPFC with transcranial direct current stimulation (tDCS) during a ...
Villa-Sánchez, Bernardo +2 more
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The dorsolateral prefrontal cortex, schizophrenia and PET
1992Central neurophysiology can be measured with PET. These measurements are providing insights into the regional abnormalities associated with schizophrenia. Cohorts of schizophrenic subjects have been studied cross-sectionally in attempts to identify common regional deficits.
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Inhibitory deficits in the dorsolateral prefrontal cortex in psychopathic offenders
Cortex, 2013Often typified as cunning social predators, psychopathic offenders show a persistent pattern of impulsive and reckless behavior, the pathophysiology of which has been related to dysfunction in the dorsolateral prefrontal cortex (DLPFC). That is, the DLPFC is important for the regulatory control of impulses and emotion as well as working memory and ...
Hoppenbrouwers, S.S. +6 more
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Regional distribution of functions in dorsolateral prefrontal cortex of the monkey
Behavioural Brain Research, 1993Single-cell responses were obtained from 352 neurons in dorsolateral prefrontal cortex (Walker's areas 9 and 46) of three monkeys. The neurons were classified functionally according to their responsiveness to visual, auditory and somatosensory stimulation, and to correlation of their activity with spontaneous eye or limb movements. A comparison between
H, Tanila +3 more
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Dorsolateral prefrontal cortex and the implicit association of concepts and attributes
NeuroReport, 2000The Implicit Association Test (IAT) examines the differential association of two object categories (e.g. flower and insect) with attribute categories (e.g. pleasant and unpleasant). When items from congruent categories (e.g. flower + pleasant) share a response key, performance is faster and more accurate than when items from incongruent categories (e.g.
Chee, M.W.L. +3 more
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The role of the dorsolateral prefrontal cortex in implicit procedural learning
Experimental Brain Research, 1996We studied the role of the dorsolateral prefrontal cortex in procedural learning. Normal subjects completed several blocks of a serial reaction time task using only one hand without or with concurrent non-invasive repetitive transcranial magnetic stimulation.
A, Pascual-Leone +3 more
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