Results 141 to 150 of about 29,170 (291)

Vegetally localized Vrtn functions as a novel repressor to modulatebmp2btranscription during dorsoventral patterning in zebrafish

, 2017
The vegetal pole cytoplasm represents a critical source of maternal signals for patterning the primary dorsoventral axis of the early embryo. Vegetally localized dorsal determinants are essential for the formation of the Spemann organizer, which ...
Yan-Jun Zhang, Ming Shao, Min Wang, De-Li Shi, Yi-Wen Ge   +4 more
core   +1 more source

From muscle fibres to muscle gears: how dynamic fascicle orientation and shape change impact skeletal muscle function

Biological Reviews, EarlyView.
ABSTRACT Skeletal muscle architectural design strongly affects force‐generating capacity and excursion range, and its functional importance to animal and human movement is well founded. Traditionally, this ‘structure–function relation’ has been inferred from architecture measurements with muscles at rest (from anatomical dissections or medical imaging ...
Matheus D. Pinto, James M. Wakeling, Javier A. Almonacid, Anthony J. Blazevich   +3 more
wiley   +1 more source

The association between neural crest‐derived glia and melanocyte lineages throughout development and disease

Developmental Dynamics, EarlyView.
Abstract Neural crest cells are a transient cell population that emerges from the dorsal neural tube during neurulation and migrates extensively throughout the embryo. Among their diverse derivatives, glial cells (such as Schwann and satellite ganglionic cells) and melanocytes represent two major lineages. In vitro studies suggested they share a common
Chaya Kalcheim
wiley   +1 more source

Brain-wide functional organization of the hippocampus along the dorsoventral axis: an optogenetic fMRI study

, 2018
Hippocampus plays a prominent role in central nervous system functions. It receives convergent projections and sends reciprocal divergent projections, forming an interactive cortico-hippocampal-cortical network. However, the precise brain-wide functional
Wong, ECS, Wang, X, Chan, RW, Hallaoui, KE, Leong, ATL, Dong, CM, Wu, EX   +6 more
core  

FIGURES 1–8. 1–5, Austrophilopterus cancellosus. 1, Entire dorsoventral male. 2, Male dorsal head. 3, Male genitalia. 4 in The genus Austrophilopterus Ewing (Phthiraptera: Philopteridae) from toucans, toucanets, and araçaris (Piciformes: Ramphastidae)

, 2005
FIGURES 1–8. 1–5, Austrophilopterus cancellosus. 1, Entire dorsoventral male. 2, Male dorsal head. 3, Male genitalia. 4, Terminal portion of male genitalia. 5, Female metanotum and dorsoventral abdomen. 6–7, A. flavirostris.
Price, Roger D., Weckstein, Jason D.
core   +1 more source

Zebrafish ventral gastrula fate map reveals neural crest progenitor domain

Developmental Dynamics, EarlyView.
Abstract Background Fate maps relate progenitor cell positions to later fates and locations of their progeny, revealing early embryonic organization. Previous zebrafish fate maps identified the origin of germ layers and derivative cell fates, but ventral gastrula progenitor domains were not fully resolved. In particular, the neural crest, a multipotent
Elaine E. Kushkowski, Victoria E. Prince
wiley   +1 more source

Evidence for functional convergence between LZTS2 and DYRK1A during craniofacial development

Developmental Dynamics, EarlyView.
Abstract Background Precise control of DYRK1A dosage is essential for embryonic development, including craniofacial morphogenesis. While LZTS2 is among the most consistently identified DYRK1A‐interacting proteins, its roles in embryonic development remain incompletely understood, and its potential contribution to craniofacial development has not been ...
Nicole Cheng, Santiago Lima, Larisa Litovchick, Amanda J. G. Dickinson   +3 more
wiley   +1 more source

Post‐ovipositional staging series of the foveate, gold‐dust day gecko, Phelsuma laticauda (Gekkota: Squamata)

Developmental Dynamics, EarlyView.
Abstract Background Disorders affecting the fovea, a specialized pit in the human retina necessary for high acuity vision, represent a significant healthcare burden across the globe. Degenerative diseases (e.g., macular degeneration) and developmental conditions (e.g., albinism and aniridia) affecting the fovea can lead to irreversible, central vision ...
Andrew E. Wegerski, Aaron H. Griffing, Courtney E. Murr, Tony Gamble, Brian P. Brooks, Robert B. Hufnagel, Ashley M. Rasys   +6 more
wiley   +1 more source

A single base‐pair variation in a limb‐specific Lhx9 cis‐regulatory region modulates HAND2‐associated posterior repression

Developmental Dynamics, EarlyView.
Abstract LIM Homeobox 9 (Lhx9) is a transcription factor involved in vertebrate limb development. Despite conserved anterior expression, its distal expression is species‐specific. In chickens, distal expression is restricted to the anterior mesoderm; in mice, it extends into posterior mesoderm.
Jeanyoung Kim, Grace Santrach, William M. Sparks, Molly Ahola, Jessica C. Britton, Novalee Erickson, Shimako Kawauchi, Eunyoung Kim, Charmaine U. Pira, Kerby C. Oberg   +9 more
wiley   +1 more source

β‐Hydroxybutyrate reduces neuronal excitability via GIRK channels

Epilepsia, EarlyView.
β‐Hydroxybutyrate decreases neuronal excitability by activating GIRK channels through HCAR2 signaling, providing a cellular mechanism that may contribute to the antiseizure effects of the ketogenic diet. Abstract Objective The ketogenic diet is used to treat drug‐resistant epilepsy, yet the molecular mechanisms coupling metabolic state to seizure ...
Soudabeh Naderi, John Williamson, Jhanvi Patel, Samikksha Kumar, Huayu Sun, Lucy Dang Nguyen, Katarzyna Rękawek, Ifrah Zawar, Jaideep Kapur   +8 more
wiley   +1 more source