Results 1 to 10 of about 252 (120)

Theta Dynamics in Rat: Speed and Acceleration across the Septotemporal Axis [PDF]

open access: yesPLoS ONE, 2014
Theta (6-12 Hz) rhythmicity in the local field potential (LFP) reflects a clocking mechanism that brings physically isolated neurons together in time, allowing for the integration and segregation of distributed cell assemblies.
James R. Hinman   +2 more
exaly   +7 more sources

Theta variation and spatiotemporal scaling along the septotemporal axis of the hippocampus [PDF]

open access: yesFrontiers in Systems Neuroscience, 2015
Hippocampal theta has been related to locomotor speed, attention, anxiety, sensorimotor integration and memory among other emergent phenomena. One difficulty in understanding the function of theta is that the hippocampus (HPC) modulates voluntary ...
Lauren L Long   +2 more
doaj   +5 more sources

Septotemporal variations in hippocampal value and outcome processing

open access: yesCell Reports, 2023
Summary: A large body of evidence indicates functional variations along the hippocampal longitudinal axis. To investigate whether and how value and outcome processing vary between the dorsal (DH) and the ventral hippocampus (VH), we examined neuronal ...
Min Whan Jung
exaly   +5 more sources

Septotemporal variation in beta-adrenergic modulation of short-term dynamics in the hippocampus

open access: yesIBRO Neuroscience Reports, 2021
Recent evidence shows a greater facilitating effect of beta-adrenergic receptors (β-ARs) on long-term synaptic plasticity in the ventral versus the dorsal hippocampus.
Athina Miliou   +3 more
doaj   +3 more sources

Late maturation of adult-born neurons in the temporal dentate gyrus.

open access: yesPLoS ONE, 2012
Hippocampal function varies along its septotemporal axis, with the septal (dorsal) pole more frequently involved in spatial learning and memory and the temporal (ventral) pole playing a greater role in emotional behaviors.
Jason S Snyder   +2 more
doaj   +2 more sources

Increased Inhibition May Contribute to Maintaining Normal Network Function in the Ventral Hippocampus of a Fmr1-Targeted Transgenic Rat Model of Fragile X Syndrome

open access: yesBrain Sciences, 2023
A common neurobiological mechanism in several neurodevelopmental disorders, including fragile X syndrome (FXS), is alterations in the balance between excitation and inhibition in the brain. It is thought that in the hippocampus, as in other brain regions,
Leonidas J. Leontiadis   +5 more
doaj   +1 more source

Acute Hippocampal Damage as a Prognostic Biomarker for Cognitive Decline but Not for Epileptogenesis after Experimental Traumatic Brain Injury

open access: yesBiomedicines, 2022
It is necessary to develop reliable biomarkers for epileptogenesis and cognitive impairment after traumatic brain injury when searching for novel antiepileptogenic and cognition-enhancing treatments.
Eppu Manninen   +9 more
doaj   +1 more source

CXCL12-mediated guidance of migrating embryonic stem cell-derived neural progenitors transplanted into the hippocampus. [PDF]

open access: yesPLoS ONE, 2010
Stem cell therapies for neurodegenerative disorders require accurate delivery of the transplanted cells to the sites of damage. Numerous studies have established that fluid injections to the hippocampus can induce lesions in the dentate gyrus (DG) that ...
Nathaniel W Hartman   +5 more
doaj   +1 more source

Bidirectional multisite seizure propagation in the intact isolated hippocampus: The multifocality of the seizure “focus”

open access: yesNeurobiology of Disease, 2006
Localizing the seizure focus is difficult and frequently, multiple sites are found. This reflects our poor understanding of the fundamental mechanisms of seizure generation and propagation. We used multisite electrophysiological recordings in two seizure
M. Derchansky   +7 more
doaj   +1 more source

Noncanonical projections to the hippocampal CA3 regulate spatial learning and memory by modulating the feedforward hippocampal trisynaptic pathway.

open access: yesPLoS Biology, 2021
The hippocampal formation (HF) is well documented as having a feedforward, unidirectional circuit organization termed the trisynaptic pathway. This circuit organization exists along the septotemporal axis of the HF, but the circuit connectivity across ...
Xiaoxiao Lin   +6 more
doaj   +1 more source

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