Results 151 to 160 of about 29,170 (291)

Early treatment prevents neuronal loss in experimental status epilepticus: A magnetic resonance spectroscopic imaging study

Epilepsia, EarlyView.
Abstract Objective In status epilepticus there are concerns that the prolonged high‐intensity electrographic seizure activity causes neuronal death and poorer outcomes. In animal models of status epilepticus, early treatment that stops the seizures prevents the later development of epilepsy.
Yue Chen, Erik J. Fernandez, Edward H. Bertram   +2 more
wiley   +1 more source

Adeno‐associated virus‐mediated restoration of NaV1.1 in targeted brain regions ameliorates epilepsy in symptomatic Dravet syndrome mice

Epilepsia, EarlyView.
Abstract Objective Dravet syndrome (DS) is a developmental and epileptic encephalopathy primarily caused by haploinsufficiency of the SCN1A gene, which encodes the alpha subunit of NaV1.1 voltage‐gated sodium channel. The disease manifests with febrile and spontaneous seizures, developmental delay, cognitive impairment, and increased risk of sudden ...
Martina Mainardi, Simone Brusco, Serena Gea Giannelli, Vania Broccoli, Gaia Colasante   +4 more
wiley   +1 more source

The translational asymmetry of corpus callosotomy: Two literatures that answered different questions

Epilepsia Open, EarlyView.
Abstract Corpus callosotomy is an established palliative operation for drug‐resistant epilepsy dominated by drop attacks, and it is performed in three extents: anterior, usually of the anterior two‐thirds; total, in one or two stages; and selective posterior, which preserves the genu and rostral body.
Vitória Bernal Cavalcanti, Paulo Henrique Pires de Aguiar   +1 more
wiley   +1 more source

Dorsoventral Patterning in Tribolium Castaneum

, 2000
In Drosophila the nuclear gradient of the maternal transcription factor Dorsal determines cell fates along the dorsoventral axis of the embryo by acting as a transcriptional activator or repressor of zygotic target genes.
Handel, K., Chen, G., Röhl, S.
core  

Development of a Zebrafish Embryo‐Based Test System for Thyroid Hormone System Disruption: 3Rs in Ecotoxicological Research

Environmental Toxicology and Chemistry, EarlyView.
Abstract There is increasing concern regarding pollutants disrupting the vertebrate thyroid hormone (TH) system, which is crucial for development. Thus, identification of TH system–disrupting chemicals (THSDCs) is an important requirement in the Organisation for Economic Co‐operation and Development (OECD) testing framework.
Lisa Gölz, Melanie Blanc‐Legendre, Maximilian Rinderknecht, Laura Behnstedt, Sara Coordes, Luisa Reger, Sacha Sire, Xavier Cousin, Thomas Braunbeck, Lisa Baumann   +9 more
wiley   +1 more source

The limb dorsoventral axis: Lmx1b's role in development, pathology, evolution, and regeneration

The limb anatomy displays well-defined dorsal and ventral compartments, housing extensor, and flexor muscles, which play a crucial role in facilitating limb locomotion and manipulation.
Castilla-Ibeas, Alejandro, Ros, María A., Zdral, Sofía, Oberg, Kerby C.   +3 more
core   +1 more source

Effect of exercise‐related nasopharyngeal disorders on upper airway function in racehorses

Equine Veterinary Journal, EarlyView.
Abstract Background Exercise‐related upper respiratory tract (URT) disorders are frequently diagnosed in racehorses. Treatment recommendations are routinely based on subjective assessment of clinical evaluation and exercising endoscopy findings. Objectives To objectively investigate how palatal instability (PI), intermittent dorsal displacement of the ...
Hanna Vermedal, Ingunn Risnes Hellings, Zoe L. Fretheim‐Kelly, Constanze Fintl, Eric Strand   +4 more
wiley   +1 more source

Effect of volume for injection of the 15th to 16th thoracic interspinous space: An ex vivo study

Equine Veterinary Journal, EarlyView.
Abstract Background Impinging (overriding) spinous processes (ISPs) are commonly identified in horses with back pain. Diagnostic analgesia is widely used as the clinical reference standard for confirming association with clinical signs of back pain, but the specificity of dorsal spinous region diagnostic analgesia remains poorly understood.
Virginia Melly, Kara A. Brown, Julie Engiles, Holly L. Stewart, Darko Stefanovski, Kathryn W. Bills, Elizabeth Davidson   +6 more
wiley   +1 more source

Correlating relative light sensitivity to retinal visual gene expression patterns in three African cichlid fish species. [PDF]

Biol Open
Potkamp G, Zhemchuzhnikova E, van Geresteijn F, Luijben JA, Munnik FA, Veldhuis TA, Maan ME, van de Zande L, Etienne RS.   +8 more
europepmc   +1 more source

Whale swimming evolution recorded in vertebral microanatomy from the Eocene to present. [PDF]

J Anat
Whale locomotion changed significantly from land‐living ancestors, via semi‐aquatic taxa, to today's fully aquatic species. The vertebral column is important for swimming, and this study focuses on the inner microanatomy of different vertebral regions.
Delsett LL, Kimball JJL, Simonsen V, Meijer HJM, Pyenson ND.   +4 more
europepmc   +2 more sources