Results 191 to 200 of about 29,170 (291)

Functional morphology and biomechanics of the locomotor apparatus in the large Late Triassic carnivore Postosuchus kirkpatricki (Archosauria: Rauisuchidae)

open access: yesJournal of Anatomy, EarlyView.
A three‐dimensional model is used to analyze the locomotor biomechanics of the large Late Triassic archosaurian reptile Postosuchus kirkpatricki. The study finds that it is more uncertain than previously concluded whether it was quadrupedal or bipedal, and plantigrade or digitigrade, but it clearly had locomotor specializations including large hindlimb
John R. Hutchinson   +6 more
wiley   +1 more source

Anatomical description of the jaw muscles and theoretical bite force assessment in South American opossums using manual and digital dissection methods

open access: yesJournal of Anatomy, EarlyView.
Manual and virtual dissections were employed to examine the masticatory muscle architecture and bite force of three South American marsupials. The organisation of the muscles differed between species, with predicted bite forces exceeding previous estimates.
Alice Melekian   +4 more
wiley   +1 more source

An Orthotopic Xenograft Model for Preclinical Evaluation of CAR T Cell Therapy in Glioblastoma. [PDF]

open access: yesCurr Protoc
Abstract Glioblastoma (GBM) is the most lethal primary brain tumor in adults, and despite intensive research efforts, effective therapeutic breakthroughs remain elusive. Consequently, the standard of care has remained largely unchanged for nearly 30 years, underscoring the need for robust preclinical models to evaluate experimental therapies.
Hübner J   +6 more
europepmc   +2 more sources

Cumulative effects of lifelong systemic excess growth hormone on postcranial skeletal morphology in adult mice

open access: yesJournal of Anatomy, EarlyView.
Our μCT‐based pilot study reveals size and shape disparity in the adult postcranial skeleton of growth‐hormone model (bGH) mice relative to wild‐type mice. bGH mice have larger and more sexually dimorphic bones, with a systemic radiodensity increase in bony sesamoids and associated, but typically uncalcified, soft tissues.
Joseph R. Groenke   +7 more
wiley   +1 more source

From sagittal to sprawled: Clavicular co‐option and the evolution of forelimb mechanics in talpines

open access: yesJournal of Anatomy, EarlyView.
Forelimb posture in Eulipotyphla divides into sagittal and sprawled groups with distinct scapular and clavicular orientations. First true rib strength scales with body mass, reflecting vertical ground reaction forces, whereas clavicular strength reflects differences in medially directed forces on the pectoral girdle, especially pronounced in highly ...
Shin‐ichi Fujiwara, Hiroaki Saito
wiley   +1 more source

Skeletons of swiftly swimming sharks: Three‐dimensional analysis of lamniform vertebral morphology and mineral architecture

open access: yesJournal of Anatomy, EarlyView.
We examined morphology, 3D arrangement, and mineral amount in cartilaginous vertebrae from four lamniform shark families (Alopiidae, Carchariidae, Cetorhinidae, and Lamnidae). We identified family‐specific mineralization trends, and regional patterning of structures along the column.
Jamie L. Knaub   +6 more
wiley   +1 more source

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