Results 71 to 80 of about 51,992 (374)
Generation of Neural Organoids and Their Application in Disease Modeling and Regenerative Medicine
Advanced Science, EarlyView.Neural organoids provide a versatile platform for neurological research. Advances in organoid technology have partially achieved human neural tissue complexity in terms of tissue structure, cell diversity, and neural signaling, offering insights into neural disorders and regenerative strategies. Technology advances from biomaterials, bio‐manufacturing,
Ruiqi Huang +4 more
wiley +1 more source
An Amygdala‐hippocampus Circuit for Endocannabinoid Modulation of Anxiety Avoidance
Advanced Science, EarlyView.This study employs three synapse‐specific endocannabinoids (eCB) probes to monitor dynamic eCB release, activate CB1Rs and knockdown 2‐AG biosynthesis enzymes in glutamatergic anterior basolateral amygdala ‐ ventral hippocampus (aBLA–vHPC) circuit. At aBLA–vHPC circuits, activation of CB1Rs reduce anxiety avoidance, and knockdown of eCB biosynthesis ...
Bao Xue +9 more
wiley +1 more source
iScience, 2023 Summary: The spinal cord possesses highly complex, finely organized cytoarchitecture guided by two dorsoventral morphogenic organizing centers. Thus, generation of human spinal cord tissue in vitro is challenging. Here, we demonstrated a novel method for
Weiwei Xue +7 more
doaj
Structural development and dorsoventral maturation of the medial entorhinal cortex
eLife, 2016 We investigated the structural development of superficial-layers of medial entorhinal cortex and parasubiculum in rats. The grid-layout and cholinergic-innervation of calbindin-positive pyramidal-cells in layer-2 emerged around birth while reelin ...
Saikat Ray, M. Brecht
semanticscholar +1 more source
Primitive roles for inhibitory interneurons in developing frog spinal cord [PDF]
, 2004 Understanding the neuronal networks in the mammal spinal cord is hampered by the diversity of neurons and their connections. The simpler networks in developing lower vertebrates may offer insights into basic organization.
Higashijima, S-I +4 more
core +2 more sources
Depth‐Customizable 3D Electrode Array for Recording Functional Connectivity in the Brain
Advanced Electronic Materials, EarlyView.In this study, a depth‐adjustable, flexible 3D multi‐shank electrode array that produces precise neural recordings at various brain depths is developed. Integrating 2D flexible electrode arrays with a modular supporting board allowed the insertion depth to be easily adjusted without re‐fabrication.
Minseok Kim +5 more
wiley +1 more source
Genetic control of organ shape and tissue polarity.
PLoS Biology, 2010 The mechanisms by which genes control organ shape are poorly understood. In principle, genes may control shape by modifying local rates and/or orientations of deformation.
Amelia A Green +4 more
doaj +1 more source
Animal Models and Experimental Medicine, EarlyView.To compensate for the fluorescence loss in rabies virus–derived neuronal tracing tools caused by non‐cytolytic immune clearance (NCLIC) in retrograde tracing, we developed a novel green‐to‐red spectral labeling (GTR) strategy based on the NCLIC phenomenon and developed a novel marker footprints mouse to support the strategy.
Yige Song +4 more
wiley +1 more source
The topology of connections between rat prefrontal, motor and sensory cortices [PDF]
, 2014 The connections of prefrontal cortex (PFC) were investigated in the rat brain to determine the order and location of input and output connections to motor and somatosensory cortex.
Agster +44 more
core +2 more sources
Animal Models and Experimental Medicine, EarlyView.A novel extraluminal silicone stent was developed and applied in a rabbit model of tracheomalacia. The stent effectively maintained airway patency and minimized tissue reaction without causing cartilage damage. This approach may offer a safe and effective alternative for treating tracheal collapse in small animals.
Yoon‐Hee Ryu +6 more
wiley +1 more source