Results 101 to 110 of about 9,342 (307)

Cyclodextrin enhances corneal tolerability and reduces ocular toxicity caused by diclofenac [PDF]

open access: yes, 2018
With advances in refractive surgery and demand for cataract removal and lens replacement, the ocular use of nonsteroidal anti-inflammatory drugs (NSAIDs) has increased. One of the most commonly used NSAIDs is diclofenac (Diclo).
Abdelkader, H   +4 more
core   +5 more sources

Risk of Benign Paroxysmal Positional Vertigo Modified by Diuretics—A Population‐Level Case‐Control Study

open access: yesOtolaryngology–Head and Neck Surgery, Volume 173, Issue 3, Page 613-625, September 2025.
Abstract Objective This study aims to characterize diuretic use among patients with and without benign paroxysmal positional vertigo (BPPV) using a population‐level database. Study Design A case‐control study. Setting TriNetX US Collaborative Network. Methods Subjects with ≥1 hospital visit between 2019 and 2024 were queried and stratified by age (18 ...
Marwin Li   +2 more
wiley   +1 more source

Toxicity and Physiological Actions of Carbonic Anhydrase Inhibitors to Aedes aegypti and Drosophila melanogaster

open access: yesInsects, 2016
The physiological role of carbonic anhydrases in pH and ion regulation is crucial to insect survival. We examined the toxic and neurophysiological effects of five carbonic anhydrase inhibitors (CAIs) against Aedes aegypti.
Sheena A. M. Francis   +3 more
doaj   +1 more source

An Ilomastat-CD Eye Drop Formulation to Treat Ocular Scarring [PDF]

open access: yes, 2017
PURPOSE: The purpose of this study was to develop a topical matrix metalloproteinase inhibitor preparation for antiscarring therapy. METHODS: The broad spectrum matrix metalloproteinase inhibitor ilomastat was formulated using 2-hydroxypropyl-β ...
Bailly, M   +5 more
core   +1 more source

Sulphonamide inhibition studies of the β-carbonic anhydrase from the bacterial pathogen Clostridium perfringens

open access: yesJournal of Enzyme Inhibition and Medicinal Chemistry, 2018
The β-carbonic anhydrases (CAs, EC 4.2.1.1) from the pathogenic bacterium Clostridium perfringens (CpeCA) was recently characterised kinetically and for its anion inhibition profile. In the search of effective CpeCA inhibitors, possibly useful to inhibit
Daniela Vullo   +4 more
doaj   +1 more source

Sustained ocular delivery of Dorzolamide-HCl via proniosomal gel formulation: in-vitro characterization, statistical optimization, and in-vivo pharmacodynamic evaluation in rabbits

open access: yesDrug Delivery, 2018
Glaucoma is the second cause of blindness worldwide. Frequent administration of traditional topical dosage forms may lead to patient incompliance and failure of treatment.
Nagwa Hussein Fouda   +3 more
semanticscholar   +1 more source

1%ドルゾラミド/0.5%チモロール配合剤での眼圧に対する3年間治療の効果 [PDF]

open access: yes
博士(医学) 乙第2841号, 著者名:Sakurako Takeda・Tatsuya Mimura・Masao Matsubara,タイトル:Effect of 3 years of treatment with a dorzolamide/timolol (1%/0.5%) combination on intraocular pressure,掲載誌:Clinical Ophthalmology (1177-5467),巻・頁・年:8巻 p.1773~1782 (2014),DOI:http ...
武田, 桜子
core   +1 more source

New RP-HPLC Method Development and Validation for Dorzolamide in Ophthalmic Dosage Form

open access: yesJournal of Analytical Methods in Chemistry, 2018
A reversed phase liquid chromatographic method with UV detection at 254 nm for dorzolamide assay in ophthalmic solutions was developed and validated. Chromatographic separation was achieved on a Zorbax SB C18 (250 mm × 4.6 mm, 5 µm) column kept at 30°C ...
Boovizhikannan Thangabalan   +2 more
doaj   +1 more source

Approaches in topical ocular drug delivery and developments in the use of contact lenses as drug-delivery devices [PDF]

open access: yes, 2017
The file attached to this record is the author's final peer reviewed version. The Publisher's final version can be found by following the DOI link.Drug-delivery approaches have diversified over the last two decades with the emergence of nanotechnologies,
Acheampong A   +17 more
core   +2 more sources

A combined analysis of five observational studies evaluating the efficacy and tolerability of bimatoprost/timolol fixed combination in patients with primary open-angle glaucoma or ocular hypertension [PDF]

open access: yes, 2013
OBJECTIVE: The aim of this study was to evaluate the safety and efficacy of a fixed combination of bimatoprost 0.03% and timolol (BTFC) in a clinical setting, in a large sample of patients with primary open-angle glaucoma or ocular hypertension and ...
Bron, Alain   +6 more
core   +3 more sources

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