Results 91 to 100 of about 432,722 (348)
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Formulation and pH-Physical Stability Evaluation of Gel and Cream of Plantago major Leaves Extract [PDF]
, 2017 Plantago major has been widely used for wound healing. This activity is supported by empirical as well as preclinical data. The aims of this study were to (1) formulate Plantago major leaves extracts (PMLE) into topical dosage forms i.e.
Fitriani, Endang Wahyu +3 more
core +2 more sources
Novel pharmaceutical dosage forms of analgesics [PDF]
Arhiv za farmaciju, 2019 Among novel pharmaceutical dosage forms of analgesics, whose number and diversity are continuously increasing over the past two decades, of particular importance are transdermal opioid analgesics (fentanyl, buprenorphine) for the treatment of chronic ...
Đekić Ljiljana, Primorac Marija
doaj
Vaginal Cream plus Vaginal Tablet Dosage Form [PDF]
, 2020 National Cancer Institute
openalex +1 more source
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Study of the Acidification of Sherry Musts With Gypsum and Tartaric Acid [PDF]
, 1993 Must acidification is a necessary operation in hot regions due to the low natural acid content of the grapes grown there. Tartaric acid is what is most usually used for this purpose.
Diez Martín, Juan +2 more
core +1 more source
Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
Analytical methods for the determination of aspirin in its combinations with clopidogrel and some statins in medications for treatment of acute coronary syndromes (ACS) [PDF]
Trends in Pharmaceutical SciencesThe combination of aspirin (ASP) and clopidogrel (CLD) has demonstrated efficacy in managing coronary syndromes, including unstable angina and myocardial infarction.
Imad Abu Reid
doaj +1 more source
Impregnated Material Dosage Form Category [PDF]
, 2020 National Cancer Institute
openalex +1 more source