Results 91 to 100 of about 191,476 (314)
The Assessment of the Intrasubject Variability in Digoxin Absorption in Man from Two Oral Dosage Forms [PDF]
, 1981 Avraham Yacobi +8 more
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Molecular Oncology, EarlyView.In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella +18 more
wiley +1 more source
The second peak in the serum levels curve after oral administration of a slow‐release quinidine dosage form: effect of food [letter] [PDF]
, 1982 Jean Spénard, G Sirois, Ma Hew Gagnon
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β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
SILYMARIN FOOD SUPPLEMENTS – ORAL SOLID DOSAGE FORMS
Scientific Study & Research: Chemistry & Chemical Engineering, Biotechnology, Food Industry, 2016 Several tablet formulations containing silymarin were developed, in order to meet the requirements of different markets. Milk thistle - Silybum marianum (L.) Gaertn – standardized extracts have proven their positive effect on liver functionality plus ...
FELICIA G. GLIGOR +5 more
doaj
Molecular Oncology, EarlyView.Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li +12 more
wiley +1 more source
DETERMINATION OF ANTAZOLINE IN DOSAGE FORMS AND WITH NAPHAZOLINE IN COMBINATION [PDF]
, 1984 S. El-Shabouri +3 more
openalex +1 more source