Results 181 to 190 of about 432,722 (348)

Developing In Vitro-In Vivo Correlation for Bicalutamide Immediate-Release Dosage Forms with the Biphasic In Vitro Dissolution Test. [PDF]

Pharmaceutics
Ozaksun NT, Incecayir T.
europepmc   +1 more source

Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly(ADP‐ribose) glycohydrolase inhibitor

FEBS Open Bio, EarlyView.
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley   +1 more source

Advancing non-sterile pediatric pharmacotherapy through automated compounding and 3D printing of ondansetron hcl dihydrate dosage forms. [PDF]

J Oncol Pharm Pract
Bahman M, Bernhardt MB, Brasher CA, Lahtinen J, Airaksinen S, Topelius NS.   +5 more
europepmc   +1 more source

New drugs and dosage forms [PDF]

, 2006

openalex   +1 more source

Libidibia ferrea extract as a promising antidiabetic agent: characterization, pre-clinical analysis and development of pharmaceutical dosage forms / Extrato de Libidibia ferrea como um promissor agente antidiabético: caracterização, análise pré-clínica e desenvolvimento de formas de dosagem farmacêutica

, 2021
Maria Joanellys dos Santos Lima, Karolynne Rodrigues de Melo, Victor de Albuquerque Wanderley Sales, Myla Lôbo de Souza, Emerson de Oliveira Silva, Wyndly Daniel Cardoso Gaião, Pedró José Rolim Neto, Maria Bernadete de Sousa Maia, Ivone Antônia de Souza, Rosali Maria Ferreira da Silva   +9 more
openalex   +1 more source

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

Science-Based Risk Assessment for the Categorization of Visual Inspection Defects of Sterile Dosage Forms. [PDF]

Pharmaceutics
Mahler HC, Folzer E, Ananthavettivelu R, Koehler J, Ferrari M, Allmendinger A.   +5 more
europepmc   +1 more source

Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham, Sahana Sathyanarayana, Charlotte B. Stewart, Robyn Iredale, Victoria Foster, Debra Galley, Mark Baker, Nicola Pavese   +7 more
wiley   +1 more source

Molecular docking study and pharmacokinetic insights of rifampicin in pure and capsule dosage forms. [PDF]

Sci Rep
Alassaf NA, Hamody AS, Jabir MS, Ghotekar S, Swelum AA.   +4 more
europepmc   +1 more source

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon, Nathalie Picard, Valeria d'Andrea, Enchi Chang, Joseph Leffler, Eleonora Centofante, Matthew Taylor, Francesca Bardi, Francesca Cavicchiolo, Takao K. Hensch, Stefano Panzeri, Chinfei Chen, Michela Fagiolini   +12 more
wiley   +1 more source