Development of the method for the pharmaceutical availability testing of clotrimazole from multiphase semi-solid vaginal dosage forms [PDF]
Introduction: The intravaginal drug administration enables treatment of the local and systemic diseases. The anatomy and physiology of a vagina provide several difficulties for drug technologists due to the small amount and continuous production of ...
Michał Smoleński +3 more
doaj +1 more source
Biowaiver monographs for immediate release solid oral dosage forms: prednisolone. [PDF]
Literature data relevant to the decision to allow a waiver of in vivo bioequivalence (BE) testing for the approval of immediate release (IR) solid oral dosage forms containing prednisolone are reviewed.
Barends, D M +8 more
core +1 more source
The characteristics of novel dosage forms [PDF]
The objective of pharmaceutical-technological development is to find a procedure of transforming an active substance (a drug) into a drug dosage form which is not only acceptable for application, but also enables the active substance to be released ...
Milić-Aškrabić Jela +1 more
doaj +1 more source
In order to save resource of active pharmaceutical ingredients and excipients, in the early stages of research, when planning an experiment, it is advisable to use data of the predicted and experimental physicochemical properties stored in different ...
B. S. Burlaka, I. F. Bielenichev
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Age-appropriate and acceptable paediatric dosage forms: Insights into end-user perceptions, preferences and practices from the Children's Acceptability of Oral Formulations (CALF) Study [PDF]
A lack of evidence to guide the design of age-appropriate and acceptable dosage forms has been a longstanding knowledge gap in paediatric formulation development.
Cram, A, Ranmal, SR, Tuleu, C
core +1 more source
Taste-Masked Pellets of Warfarin Sodium: Formulation towards the Dose Personalisation
The bitter drug, warfarin, has a narrow therapeutic index (NTI) and is used in paediatrics and geriatrics. The aim of this feasibility study was to formulate the taste-masked warfarin-containing pellets to be applicable for dose personalisation and to ...
Lakija Kovalenko +3 more
doaj +1 more source
Formulation and Characterization of Felodipine as an Oral Nanoemulsions
Felodipine is a calcium-channel blocker with low aqueous solubility and bioavailability. Lipid dosage forms are attractive delivery systems for such hydrophobic drug molecules.
Sumaya B. Hamed, Shaimaa N. Abd Alhammid
doaj +1 more source
Using microcrystalline cellulose (MCC) with plastic behaviour and calcium phosphate anhydrous (CaHPO4) with brittle behaviour under compaction is very popular in the pharmaceutical industry for achieving desirable structural–mechanical properties of ...
Valentyn Mohylyuk +3 more
doaj +1 more source
Novel pharmaceutical dosage forms of analgesics [PDF]
Among novel pharmaceutical dosage forms of analgesics, whose number and diversity are continuously increasing over the past two decades, of particular importance are transdermal opioid analgesics (fentanyl, buprenorphine) for the treatment of chronic ...
Đekić Ljiljana, Primorac Marija
doaj +1 more source
Development and optimization of a novel sustained-release dextran tablet formulation for propranolol hydrochloride [PDF]
A novel oral controlled delivery system for propranolol hydrochloride (PPL) was developed and optimized. The in vitro dissolution profiles of sustained-release matrix tablets of racemic PPL were determined and compared with the United States Pharmacopeia
Bataille, Bernard +5 more
core +2 more sources

