Results 31 to 40 of about 420,256 (310)

Development of Orally Disintegrating Tablets of Standardized Rhodiola rosea Extract

Pharmaceuticals
Background/Objectives: Rhodiola rosea L. (Crassulaceae), a perennial adaptogenic herb native to Northern Europe, Asia, and North America, is renowned for its therapeutic properties attributed to phenolic compounds including flavonoids, phenylethanoids ...
Oxana Brante, Rihards Talivaldis Bagons, Santa Niedra, Austris Mazurs, Baiba Mauriņa, Jurga Bernatoniene, Konstantins Logviss   +6 more
doaj   +1 more source

Stability of Extemporaneously Prepared Rufinamide Oral Suspensions [PDF]

, 2010
Background: Rufinamide is an oral antiepileptic drug indicated for adjunctive therapy in treating generalized seizures associated with Lennox-Gastaut syndrome. Currently, rufinanide is available as 200-mg and 400-mg tablets. A liquid dosage form does not
Best, Robert, Hutchinson, David, Liou, Yayin, Zhao, Fang   +3 more
core   +2 more sources

Predicting Drug Loading Capacity for PLA-Amorphous Drug System Using Hansen Solubility Parameters

Pharmaceutics
Objective: In this work, we look at Hansen solubility parameters (HSPs) to predict drug miscibility with polymers, in order to create a saturated amorphous drug phase.
Artūrs Paulausks, Artjoms Iljičevs, Jurga Bernatoniene, Līga Pētersone, Konstantīns Logviss   +4 more
doaj   +1 more source

Etodolac Softgels: Feasibility Assessment and Considerations for Lipid-Based Formulations of a highly hydrophobic drug

Zagazig Journal of Pharmaceutical Sciences, 2017
Oral lipid-based formulations provide a significant opportunity to address the poor and variable gastrointestinal absorption associated with poorly water soluble drugs.
Ahmed N. Allam , Ibrahim A. Komeil , Ossama Abdallah   +2 more
doaj   +1 more source

Tobacco: Its Conventional and Modern Dosage Forms in Medication

Bezmiâlem Science, 2022
Tobacco is one of the most planted products in worldwide and the whole Nicotiana tabacum L. plant, its leaves, flowers, seeds or roots, and individual chemical compounds have medicinal uses such as as sedative, diuretic, or expectorant.
İmren ESENTÜRK-GÜZEL, Evren Algın YAPAR, Rakesh K SINDHU, Harnoor KAUR, Bilge Ahsen KARA   +4 more
doaj   +1 more source

The HIT Network for Children and Adolescents With CNS Tumors Facilitates Improvements of Diagnostic Assessments, Multimodal Treatments, Individual Counseling, and Research in Germany, Austria, and Switzerland

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background The HIT network was established in 2000 to create a population‐based structure aiming to improve survival rates and reduce late effects for children with central nervous system (CNS) tumors by conducting comprehensive clinical trials.
Stefan Rutkowski, Michael C. Frühwald, Gudrun Fleischhack, Stephan Tippelt, Pablo Hernáiz‐Driever, Olaf Witt, Astrid Gnekow, Christof Kramm, Matthias Eyrich, Johannes E. A. Wolf, Hermann Müller, Carsten Friedrich, Uwe R. Kordes, Denise Obrecht‐Sturm, Petra Ketteler, Barbara von Zezschwitz, Pascal Johann, Dominik Sturm, Karoline Nemes, Stefan Schönberger, Till Milde, Brigitte Bison, Monika Warmuth‐Metz, Torsten Pietsch, Ulrich Schüller, Arend Koch, David Capper, Martin Hasselblatt, Christian Thomas, Christian Hagel, Stefan M. Pfister, Felix Sahm, David T. W. Jones, Martin U. Schuhmann, Jürgen Krauss, Pedram Emami, Ahmed El Damaty, Rolf D. Kortmann, Rudolf Schwarz, Jürgen Debus, Mechthild Krause, Fabian Pohl, Holger Ottensmeier, Lisa Bußenius, Katja Baust, Andreas Faldum, Cecile Ronckers, Desiree Grabow, Martin Benesch, Thomas Perwein, Karin Dieckmann, Irene Slavc, Johannes Gojo, Nicolas U. Gerber, André O. von Bueren, Katrin Scheinemann, Gabriele Calaminus, Beate Timmermann, Ulrich‐Wilhelm Thomale, Martin Mynarek   +59 more
wiley   +1 more source

Antibacterial Activity of Novel Agent N-2-Hydroxypropyl Trimethyl Ammonium Chloride Chitosan against Streptococcus mutans

Molecules
Dental caries (DC) is one of the most common oral diseases and is mainly caused by Streptococcus mutans (S. mutans). The use of antibiotics against S. mutans usually has side effects, including developing resistance.
Yuan Gao, Xiaochen Gong, Qicheng Ruan, Chunjing Zhang, Kai Zhao   +4 more
doaj   +1 more source

The research on creation the dosage form based on 3-(4-nitrophenyl)-5-(nonylsulfonyl)-1,2,4-triazol-4-amine

Zaporožskij Medicinskij Žurnal, 2014
The search of new biologically active substances, which can be potential drugs with low toxicity and high levels of biological effects, is one of the major aims of modern medicine and pharmacy. Chemical modification of heterocyclic molecules, such as 1,2,
M. A. Shcherbak, A. G. Kaplaushenko, N. N. Maletskiy, Ye. A. Sharaya   +3 more
doaj   +1 more source

Pilot trial of fk 506 in the management of steroid-resistant nephrotic syndrome [PDF]

, 1993
Seven patients with steroid-resistant nephrotic syndrome were treated with FK 506 monotherapy. Four patients were children with focal sclerosing glomerulonephritis (FSGS).
Ellis, D, Igdal, H, McCalley, J, Shapiro, R, Shapiro, R, Starzl, TE, Starzl, TE, Starzl, TE, Tzakis, A, Tzakis, A   +9 more
core   +1 more source

Imaging of High‐Risk Neuroblastoma: Recommendations From SIOPEN Radiology and Nuclear Medicine Specialty Committees

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Neuroblastoma is the most common extracranial solid tumor in early childhood. Its clinical behavior is highly variable, ranging from spontaneous regression to fatal outcome despite intensive treatment. The International Society of Pediatric Oncology Europe Neuroblastoma Group (SIOPEN) Radiology and Nuclear Medicine Specialty Committees ...
Annemieke Littooij, Catia Olianti, Herve Brisse, Pier Luigi Di Paolo, Maria Garganese, Tejas Kapadia, Jurgen Schaefer, Hugh Wallace, Simon Wan, Bart de Keizer, Irmina Sefic Pasic, Julian Rogasch   +11 more
wiley   +1 more source