Results 61 to 70 of about 191,476 (314)
Introduction: Education of health care providers regarding the proper use of dosage forms is inadequate, contributing to prescription errors. Objectives : The objective of this study is to assess the knowledge of interns regarding the dosage forms and ...
Mahendra Mahadu Gaikwad+3 more
doaj +1 more source
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine+10 more
wiley +1 more source
Determination of visible particles in parenteral dosage forms and ophthalmic dosage forms
The present article describes the approaches to the choice of methods for assessing the content of visible particles in parenteral and ophthalmic dosage forms, recognized in general pharmacopoeia monograph «Visible particles in parenteral dosage forms ...
Yu. V. Olefir+7 more
doaj
Novel pharmaceutical dosage forms of analgesics [PDF]
Among novel pharmaceutical dosage forms of analgesics, whose number and diversity are continuously increasing over the past two decades, of particular importance are transdermal opioid analgesics (fentanyl, buprenorphine) for the treatment of chronic ...
Đekić Ljiljana, Primorac Marija
doaj
Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte+10 more
wiley +1 more source
In-vivo Monitoring of Dosage Forms
Abstract The use of imaging techniques including gamma scintigraphy to follow the behaviour of drug formulations has revolutionized our knowledge of absorption and distribution in drug delivery. The development of gamma camera techniques as physiological tools to explore organ function became routine by the mid-seventies.
openaire +3 more sources
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song+11 more
wiley +1 more source
Analytical methods for the determination of aspirin in its combinations with clopidogrel and some statins in medications for treatment of acute coronary syndromes (ACS) [PDF]
The combination of aspirin (ASP) and clopidogrel (CLD) has demonstrated efficacy in managing coronary syndromes, including unstable angina and myocardial infarction.
Imad Abu Reid
doaj +1 more source
THE ACTION OF ALLELIC FORMS OF THE GENE A IN MAIZE. I. STUDIES OF VARIABILITY, DOSAGE AND DOMINANCE RELATIONS. THE DIVERGENT CHARACTER OF THE SERIES [PDF]
John R. Laughnan
openalex +1 more source
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton+17 more
wiley +1 more source