Results 91 to 100 of about 8,528,698 (291)
Test Of Homogeneity For Umbrella Alternatives In Dose-Response Relationship For Poisson Variables [PDF]
, 2003 This article concerns the testing and estimation of a dose-response effect in medical studies. We study the statistical test of homogeneity against umbrella alternatives in a sequence of Poisson distributions associated with an ordered dose variable.
Ji, Ming, Xiong, Chengjie, Yan, Yan
core +2 more sources
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
The dose-response relationship for cardiovascular disease is not necessarily linear
Radiation Oncology, 2017 The probability for a complication after radiotherapy is usually a function of dose and volume in the organ or tissue of interest. In most epidemiological studies the risk for a complication is stratified in terms of dose, but not irradiated volume.
U. Schneider, Marina Ernst, M. Hartmann
semanticscholar +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Chronic periodontitis and smoking Prevalence and dose-response relationship
Saudi Medical Journal, 2016 Objectives: To determine the prevalence and dose-response relationship of chronic periodontitis among smokers in Pakistan. Methods: This is a cross-sectional study among participants seeking dental care in Karachi Medical and Dental College, Karachi ...
Shahrukh Khan, Taimur Khalid, K. Awan
semanticscholar +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
A U-shaped dose–response of carbohydrate–protein supplementation on rowing performance
Frontiers in NutritionBackground and aimCo-ingestion of carbohydrate and protein supplement (CHO–PRO) is a common strategy to enhance endurance performance. However, the optimal dose–response relationship has not been established, which limits evidence-based nutritional ...
Xiangyu Wang, Xiangyu Wang, Hao Wu
doaj +1 more source
Practical considerations for optimal designs in clinical dose finding studies [PDF]
Determining an adequate dose level for a drug and, more broadly, characterizing its dose response relationship, are key objectives in the clinical development of any medicinal drug. If the dose is set too high, safety and tolerability problems are likely
Bretz, Frank +2 more
core
Effects of the Shape of the Radiation Dose-Response Curve on Public Acceptance of Radiation and Nuclear Energy [PDF]
, 2002 [Excerpt] “The public generally accepts the premise that exposure to radiation can have an undesirable effect. Furthermore, it believes that as the radiation dose increases, the magnitude of the effect will increase.
Fentiman, Audeen W.
core +1 more source
An investigation of thresholds in air pollution-mortality effects [PDF]
, 2004 In this paper we introduce and implement new techniques to investigate threshold effects in air pollution-mortality relationships. Our key interest is in measuring the dose-response relationship above and below a given threshold level where we allow for ...
Clyde +36 more
core +1 more source