Results 111 to 120 of about 8,423,709 (341)

Dose–Response Relationship between Physical Workload and Specific Shoulder Diseases—A Systematic Review with Meta-Analysis [PDF]

, 2020
Andreas Seidler, Karla Romero Starke, Alice Freiberg, Janice Hegewald, Albert Nienhaus, Ulrich Bolm‐Audorff   +5 more
openalex   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Which is the Right Dose of EU Cohesion Policy for Economic Growth? [PDF]

The current empirical literature on the impact of EU Cohesion Policy on the economic growth rates of the European regions mainly relies on functional form assumptions.
Hagen, Tobias, Mohl, Philipp
core  

Can variability in the effect of opioids on refractory breathlessness be explained by genetic factors? [PDF]

, 2015
© 2015, BMJ Publishing Group. All rights reserved. Objectives: Opioids modulate the perception of breathlessness with a considerable variation in response, with poor correlation between the required opioid dose and symptom severity. The objective of this
Currow, David C., Ekstrom, Magnus, Ekström, Magnus, Johnson, Miriam J., Kaasa, S., Kaasa, Stein, Klepstad, Pal, Klepstad, Päl, Quinn, S., Quinn, Stephen, Somogyi, Andrew A.   +10 more
core   +1 more source

The dose-response relationship for cardiovascular disease is not necessarily linear

Radiation Oncology, 2017
The probability for a complication after radiotherapy is usually a function of dose and volume in the organ or tissue of interest. In most epidemiological studies the risk for a complication is stratified in terms of dose, but not irradiated volume.
U. Schneider, Marina Ernst, M. Hartmann
semanticscholar   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Resposta imune humoral de cães à vacina inativada, de cérebro de camundongos lactentes, utilizada nas campanhas anti-rábicas no Brasil Humoral immune response of dogs to the inactivated suckling mouse brain vaccine utilized in anti-rabies campaigns in Brazil

Revista de Saúde Pública, 1997
INTRODUÇÃO: A campanha anti-rábica no Brasil é realizada anualmente utilizando a vacina de cérebro de camundongos lactentes Fuenzalida-Palacios. A resposta imune humoral de cães vacinados durante as campanhas foi analisada objetivando avaliar se os cães ...
Marilene F. Almeida, Elizabeth A. C. Aguiar, Luzia A. F. Martorelli, Douglas Presotto, Marcelo M. Brandão, Octávio A. C. Pereira   +5 more
doaj   +1 more source

Western corn rootworm pyrethroid resistance confirmed by aerial application simulations of commercial insecticides [PDF]

, 2019
The western corn rootworm (Diabrotica virgifera virgifera LeConte) (WCR) is a major insect pest of corn (Zea mays L.) in the United States (US) and is highly adaptable to multiple management tactics.
Fritz, Bradley K., Hoffmann, Wesley C., Kruger, Greg, Meinke, Lance J., Peterson, Julie A., Souza, Dariane, Vieira, Bruno C.   +6 more
core   +1 more source

An investigation of thresholds in air pollution-mortality effects [PDF]

, 2004
In this paper we introduce and implement new techniques to investigate threshold effects in air pollution-mortality relationships. Our key interest is in measuring the dose-response relationship above and below a given threshold level where we allow for ...
Clyde, Daniels, Delfino, Dockery, Dominici, Draper, Fairly, Fernandez, Fernandez, Gary Koop, Hodges, Hoeting, Hurley, Koop, Koop, Lim, Lise Tole, Madigan, Meng, Ordieres, Ostro, Pope, Raftery, Schwartz, Schwartz, Schwartz, Schwartz, Schwartz, Schwartz, Schwartz, Schwartz, Schwartz, Schwartz, Schwartz, Schwartz, Smith, Xu   +36 more
core   +1 more source

Dose-response Relationship of Serum Uric Acid with Metabolic Syndrome and Non-alcoholic Fatty Liver Disease Incidence: A Meta-analysis of Prospective Studies

Scientific Reports, 2015
Emerging evidence has shown that serum uric acid (SUA) elevation might cause metabolic derangements, including metabolic syndrome (MetS) and non-alcoholic fatty liver disease (NAFLD); however, magnitude of the risk has not been quantified.
Zhengtao Liu, S. Que, Lin Zhou, Shusen Zheng   +3 more
semanticscholar   +1 more source