Results 71 to 80 of about 8,528,698 (291)

Rat mammary carcinogenesis following neutron- or X-radiation [PDF]

, 1974
Female 61 to 63 - day - old Sprague-Dawley rats were exposed once to a single dose of either 0.43 - MeV neutrons or 250 - kVX - rays . For neutrons 23 rats were exposed in plastic tubes rotated around and 31 c m from a water-cooled tritium impregnated ...
Bond, V. P., Brown, R. D., Goodman, L. J., Kellerer, Albrecht M., Mills, R. E., Rao, A. R., Rossi, H. H., Shanley, J. P., Shellabarger, C. J.   +8 more
core   +1 more source

Dose-Response Relationship Between Long-Term Systemic Corticosteroid Use and Related Complications in Patients with Severe Asthma

Journal of Managed Care & Specialty Pharmacy, 2016
BACKGROUND: Systemic corticosteroids are a leading cause of drug-related complications, yet little has been done to quantify the dose-response relationship between systemic corticosteroid exposure and complications in patients with severe asthma ...
Anand A. Dalal, M. Duh, L. Gozalo, M. Robitaille, F. Albers, S. Yancey, H. Ortega, M. Forshag, Xiwu Lin, P. Lefebvre   +9 more
semanticscholar   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Correlation between cardiometabolic index and stroke in middle-aged and older adults

Zhongguo linchuang yanjiu
Objective To explore the relationship between cardiac metabolic index (CMI) and stroke in middle-aged and elderly individuals based on a large sample cohort study. Methods Data were obtained from the China Health and Retirement Longitudinal Study (CHARLS)
YU Yang, SHA Ou
doaj   +1 more source

Association between dietary magnesium intake and risk of hypertension in Chinese adults

环境与职业医学, 2022
BackgroundMagnesium plays an important physiological role in human, but the association between dietary magnesium intake and the risk of hypertension is unclear. Few studies have reported the dose-response relationship in Chinese population.
Liusen WANG, Huijun WANG, Zhihong WANG, Hongru JIANG, Weiyi LI, Shaoshunzi WANG, Lixin HAO, Bing ZHANG, Gangqiang DING   +8 more
doaj   +1 more source

Estimating the impact of city-wide Aedes aegypti population control: An observational study in Iquitos, Peru. [PDF]

, 2019
During the last 50 years, the geographic range of the mosquito Aedes aegypti has increased dramatically, in parallel with a sharp increase in the disease burden from the viruses it transmits, including Zika, chikungunya, and dengue.
Astete, Helvio, Halsey, Eric S, Kitron, Uriel, Kochel, Tadeuz J, Morrison, Amy C, Perkins, T Alex, Reiner, Robert C, Scott, Thomas W, Sihuincha, Moises, Smith, David L, Stancil, Jeffrey D, Stoddard, Steven T, Vazquez-Prokopec, Gonzalo M   +12 more
core   +2 more sources

Dose-Response Relationship between Dietary Magnesium Intake and Risk of Type 2 Diabetes Mellitus: A Systematic Review and Meta-Regression Analysis of Prospective Cohort Studies

Nutrients, 2016
The epidemiological evidence for a dose-response relationship between magnesium intake and risk of type 2 diabetes mellitus (T2D) is sparse. The aim of the study was to summarize the evidence for the association of dietary magnesium intake with risk of ...
X. Fang, Hedong Han, Mei Li, Chun-Yu Liang, Z. Fan, J. Aaseth, Jia He, S. Montgomery, Yang Cao   +8 more
semanticscholar   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Comparative effective dose of ciprofol and propofol in suppressing cardiovascular responses to tracheal intubation

Scientific Reports
Ciprofol, a novel γ-aminobutyric acid receptor agonist, outperforms propofol with minimal cardiovascular effects, higher potency, reduced injection pain, and a broader safety margin.
Min Liao, Xiao-Ru Wu, Jia-Ning Hu, Xing-Zhou Lin, Tang‑yuan‑meng Zhao, Hu Sun   +5 more
doaj   +1 more source

Dose-response relationship and low dose extrapolatioin in chemical carcinogenesis [PDF]

, 2017
Data supporting various dose-response relationships in chemical carcinogenesis are summarized. General principles are derived to explain the relationships between exposure dose, DNA adduct level, induction of genetic changes, and tumor incidence.
Lutz, Werner K.
core