Results 51 to 60 of about 7,945,859 (267)

THE IMPACT OF OCCLUSION THERAPY AND PREDICTORS ON AMBLYOPIA DOSE-RESPONSE RELATIONSHIP AND SUCCESS OUTCOMES

, 2021
Amblyopia is a decrease in visual acuity caused by abnormal binocular interaction or pattern vision deprivation in one or both eye(s) with no organic abnormalities which is reversible by therapeutic measures. Current research on amblyopia treatment lacks
White, Emily
core  

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

The U-Shaped Relationship Between Serum Bicarbonate Levels and 28-Day Mortality in Patients With Sepsis: A Retrospective Cohort Study of MIMIC-IV Database

Dose-Response
Background The elevated mortality rate associated with sepsis is a primary global health concern. The correlation between bicarbonate levels and mortality risk in sepsis remains unclear.
Minghao Liang, Feilong Guan, Lili Sun, Wenjing Xi, Hongling Jia, Yifei Xu, Minyan Jin, Xianhai Chen, Di Huang, Zhanjun Qiu   +9 more
doaj   +1 more source

Isolation and Detection Technologies of Extracellular Vesicles and Application on Cancer Diagnostic

Dose-Response, 2019
The vast majority of cancers are treatable when diagnosed early. However, due to the elusive trace and the limitation of traditional biopsies, most cancers have already spread widely and are at advanced stages when they are first diagnosed, causing ever ...
Chunyan Ma, Fan Jiang, Yifan Ma, Jinqiao Wang, Hongjuan Li, Jingjing Zhang   +5 more
doaj   +1 more source

Dose-response relationships for the onset of avoidance of sonar by free-ranging killer whales [PDF]

, 2014
The authors acknowledge the support of the MASTS pooling initiative (The Marine Alliance for Science and Technology for Scotland) in the completion of this study.
Samarra, Filipa Isabel Pereira, Paul J. Wensveen, Petter H. Kvadsheim, Antunes, Ricardo Nuno, Tyack, Peter Lloyd, Filipa I. P. Samarra, Ana Catarina Alves, Alves, Ana Catarina De Carvalho, Kleivane, Lars, Lam, Frans-Peter A., Ricardo N. Antunes, Miller, Patrick, Wensveen, Paulus Jacobus, Patrick J. O. Miller, Kvadsheim, Petter H., Ainslie, Michael A., Len Thomas, Frans-Peter A. Lam, Michael A. Ainslie, Lars Kleivane, Peter L. Tyack, Thomas, Len   +21 more
core   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Adenosine Concentration Determination for Tumor Microenvironment Simulation

Dose-Response
Objectives We aimed to investigate the concentration of adenosine (ADO) in the tumor microenvironment (TME), focusing on its potential to modulate tumor cells and natural killer (NK) cells, thereby facilitating tumor immune escape. Methods In this study,
Chun Chen, Chuanpeng Yang, Shuning Hu, Wenjie Nie, Sudan Ye, Minghao Lu, Xingjie Xu, Huajun Hu   +7 more
doaj   +1 more source

Summary of Dose-Response Modeling for Developmental Toxicity Studies

, 2008
Developmental toxicity studies are an important area in the field of toxicology. Endpoints measured on fetuses include weight and indicators of death and malformation.
Shesh N. Rai, Daniel L. Hunt, Chin-Shang Li   +2 more
core   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Effect of Low Doses of Low-Let Radiation on the Innate Anti-Tumor Reactions in Radioresistant and Radiosensitive Mice

Dose-Response, 2012
BALB/c and C57BL/6 mice differ in their Th1/Th2 lymphocyte and M1/M2 macrophage phenotypes, radiosensitivity, and post-irradiation tumor incidence. In this study we evaluated the effects of repeated low-level exposures to X-rays on the development of ...
Ewa M. Nowosielska, Aneta Cheda, Jolanta Wrembel-Wargocka, Marek K. Janiak   +3 more
doaj   +1 more source