Results 241 to 250 of about 707,752 (308)

The establishment of an expected concentration reference range for eltrombopag in the individualized treatment of pediatric immune thrombocytopenia. [PDF]

Front Pharmacol
Wang N, Dong S, Sun Y, Liu J, Wang Z, Ma J, Wang X, Wu R, Cheng X.   +8 more
europepmc   +1 more source

Transducer Materials Mediated Deep Brain Stimulation in Neurological Disorders

Advanced Functional Materials, EarlyView.
This review discusses advanced transducer materials for improving deep brain stimulation (DBS) in neurological disorders. These materials respond to light, ultrasound, or magnetic fields, enabling precise, less invasive neuromodulation. Their stimulus‐responsive properties enhance neural control and adaptive therapy, paving the way for next‐generation ...
Di Zhao, Zhengyang Cao, Guangjun Zhong, Limin Shi, Junxia Xie, Jianhua Hao   +5 more
wiley   +1 more source

Benchmarking of dimensionality reduction methods to capture drug response in transcriptome data. [PDF]

Sci Rep
Kwon Y, Park S, Park S, Lee H.
europepmc   +1 more source

Machine Learning Guided Design of Nerve‐On‐A‐Chip Platforms with Promoted Neurite Outgrowth

Advanced Functional Materials, EarlyView.
Compared to labor‐intensive trial‐and‐error experimentation, a machine learning (ML)‐guided workflow, incorporating cell viability assays, data augmentation, ensemble modeling, and model interpretation, is developed to accelerate nerve‐on‐a‐chip optimization and uncover data‐driven design principles.
Tsai‐Chun Chung, Chu‐Chun Liang, Min‐Wei Huang, Tianle Chen, Joshua M. Little, Snehi Shrestha, Yi‐Chen Ethan Li, I‐Chi Lee, Po‐Yen Chen   +8 more
wiley   +1 more source

Comprehensive Safety Exposure-Response Analysis to Support Ritlecitinib Dose Selection. [PDF]

CPT Pharmacometrics Syst Pharmacol
Huh Y, Qiu R, Prybylski J, Wojciechowski J, Wang Y, Purohit VS.   +5 more
europepmc   +1 more source

Flux‐Regulated Crystallization of Perovskites Using Machine Learning‐Predicted Solvent Evaporation Rates for X‐Ray Detectors

Advanced Functional Materials, EarlyView.
By integrating machine learning into flux‐regulated crystallization (FRC), accurate prediction of solvent evaporation rates in real time, improving crystallization control and reducing crystal growth variability by over threefold, is achieved. This enhances the reproducibility and quality of perovskite single crystals, leading to reproducible ...
Tatiane Pretto, Sergey Dayneko, Antoine Pavesic Junior, Nicholas Sandor, Alexander Hart, Yuki Haruta, Magdalena Bazalova‐Carter, Marcos J. L. Santos, Makhsud I. Saidaminov   +8 more
wiley   +1 more source

Modulating Oxide‐Based Quantum Materials by Ion Implantation

Advanced Functional Materials, EarlyView.
This review highlights how ion implantation, a well developed chip‐technology, enables targeted modulation of oxide‐based quantum materials. This includes tuning of metal‐insulator transitions, magnetism, and superconductivity through selective doping, defect creation, and induced lattice strain. Abstract Ion implantation has emerged as a powerful tool
Andreas Herklotz, Thomas Zac Ward, Shengqiang Zhou   +2 more
wiley   +1 more source

Semi-Mechanistic Population Pharmacokinetic/Pharmacodynamic (PK/PD) Modeling of Dupilumab on Pre-Bronchodilator Forced Expiratory Volume in 1 Second (FEV₁) in Uncontrolled Moderate-To-Severe Asthma. [PDF]

CPT Pharmacometrics Syst Pharmacol
Zhang L, Davis JD, Kanamaluru V, Xu C.
europepmc   +1 more source

Functional Hydrogel for Modulating Lipid Droplets and Neuroinflammation in Head Injury

Advanced Functional Materials, EarlyView.
After TBI, elevated cholesterol levels in activated microglia lead to the accumulation of cholesterol esters in lipid droplets, exacerbating neuroinflammation. A β‐cyclodextrin‐conjugated GelMA (βCD‐GelMA) hydrogel is developed to promotes cholesterol efflux and reduces LDL influx, thereby alleviating intracellular cholesterol and lipid droplet buildup.
Feixiang Chen, Yvonne Shen, Yutong Shao, Tenghuan Ge, Haowen Qiao, Shangzhou Xia, Yafei Qu, Yuanpu Chiu, Ying Qin, Zhen Zhao   +9 more
wiley   +1 more source

Population Pharmacokinetics and Exposure-Response Relationships of Maribavir in Transplant Recipients With First Episode or Refractory Cytomegalovirus. [PDF]

CPT Pharmacometrics Syst Pharmacol
Sun K, Jomphe C, Gosselin NH, Pheng L, Durairaj C, Hang Y, Bhattacharya I.   +6 more
europepmc   +1 more source