Results 141 to 150 of about 11,936,984 (295)

DOSE-RESPONSE RELATIONSHIPS IN RADIATION INDUCED MUTATION. SATURATION EFFECTS IN STREPTOMYCES [PDF]

Genetics, 1954
H B, Newcombe, J F, McGregor
openaire   +2 more sources

TET1 Inhibition Promotes Therapeutic Sensitivity in TP53‐Mutant GBM by Influencing Genome Fragility and Altering TAMs Biology

Advanced Science, EarlyView.
In TP53mut GBM cells, reduced P53 function is associated with increased TET1 expression. Genetic or pharmacological inhibition of TET1 correlates with genome fragility, including DNA damage, cellular senescence, telomere shortening, and reactive oxygen species accumulation, which may contribute to increased efficacy of antitumor therapy.
Zhuonan Pu, Jinqiu Liu, Yuxuan Deng, Shuyu Hao, Xiaoli Zhang, Mingxu Yang, Chao Guo, Chao Du, Yingdan Chen, Tai Sun, Nan Ji, Zhengping Zhuang, Jie Feng   +12 more
wiley   +1 more source

Somatic Evolution of a Germline Antibody Expands its Breadth to Neutralize Early SARS‐CoV‐2 Omicron Variants

Advanced Science, EarlyView.
Engineering of the 148‐germline (148‐GL) antibody reveals a roadmap for overcoming SARS‐CoV‐2 viral escape. By introducing four specific somatic hypermutations, the resulting 148‐M4 variant restores potent neutralization against Omicron BA.1 and BA.4/5.
Huibin Lv, Ziqi Feng, Qi Wen Teo, Chunke Chen, Akshita B. Gopal, Danbi Choi, Timothy J. C. Tan, Yun Sang Tang, Lewis Siu, Armita Nourmohammad, Roberto Bruzzone, Ian A. Wilson, Meng Yuan, Nicholas C. Wu, Chris K. P. Mok   +14 more
wiley   +1 more source

Tumour SUVmean and volume relates to its radiation absorbed dose. [PDF]

EJNMMI Rep
Kao YH.
europepmc   +1 more source

Radiation-induced leukaemia in spondylitics: dose-response relationships.

BMJ, 1982
D, Papworth, J, Vennart
openaire   +3 more sources

Neuron‐Targeted Exosomal Delivery of siRNA Against RIPK3 Slows Neurodegenerative Progression in Alzheimer's Disease

Advanced Science, EarlyView.
Engineered exosomal siRNA delivery platform enables systemic, neuron‐targeted RNA transport across the blood–brain barrier. Surface functionalization with rabies virus glycoprotein‐derived peptide facilitates receptor‐mediated transcytosis, achieving efficient cytosolic delivery and robust gene silencing. Targeting RIPK3 suppresses necroptosis, reduces
Chi Zhang, Jiaqi Zhang, Yuzhi Wang, Yaodong Wang, Peng Lin, Yanling Wang, Zixuan Tang, Jintai Yu, Qin Zhou, Feiyun Cui   +9 more
wiley   +1 more source

Radiation Exposure and Cancer Mortality in Populations Living Around the Semipalatinsk Nuclear Test Site in Kazakhstan. [PDF]

Int J Environ Res Public Health
Dyussupov A, Kissina R, Chaizhunussova N, Shabdarbayeva D, Orekhov A, Smailova Z, Massabayeva M, Baibussinova A, Lipikhina A, Brait Y, Klivenko A, Apbassova S, Batenova G, Lepesbayev M, Kozhanova S, Izdenov A, Dosmagambetova R, Pivina L.   +17 more
europepmc   +1 more source

Hollow Cu2O Nanozymes Enhance Probiotic Therapy for Colitis via Redox Homeostasis and TXNIP/NLRP3 Inflammasome Inhibition

Advanced Science, EarlyView.
Hollow cuprous oxide (H‐Cu2O) nanozymes feature enlarged catalytic surfaces for superior reactive oxygen species (ROS) scavenging. By efficiently neutralizing mucosal ROS, H‐Cu2O directly suppresses the TXNIP/NLRP3 inflammasome axis and restores intestinal epithelial barrier integrity.
Guangzhao Wang, Jialing Cao, Pengfei Li, Yujie Wang, Shiqi Lu, Kangliang Sheng, Shan Gao, Yongzhong Wang   +7 more
wiley   +1 more source

Review and revision of empirical critical loads and dose-response relationships

, 2011
The workshop on the review and revision of empirical critical loads and dose response relationships was held under the Convention on Long-range Transboundary Air Pollution, in Noordwijkerhout, from 23-25 June 2010.
Tomassen, Hilde, Power, Sally A. (R17014), Bobbink, Roland, Weijters, Maaike, Schütz, Kirsten, Nordin, Annika, Strengbom, Joachim, Braun, Sabine   +7 more
core  

Quantitative Cherenkov-excited fluorescence emission dosimetry for HDR Co-60 brachytherapy: Calibration and planar validation against TPS. [PDF]

J Appl Clin Med Phys
Yedekci Y, Enkavi MF, Yildiz F.
europepmc   +1 more source