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The dose-response relationship for tumourigenesis by UV radiation in the region 311 – 312 nm
Journal of Photochemistry and Photobiology B: Biology, 1988Groups of hairless mice were irradiated daily with Philips TL01 UVB sources. This type of lamp has become available recently and was developed for UVB phototherapy of psoriasis. The TL01 emits radiation in a narrow band around 311-312 nm. Tumours developed on all animals.
Sterenborg, H. J. +2 more
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Radiation dose-response relationships
2018Clinical radiobiology is a field of medical research concerned with the relationship between a given physical absorbed dose of radiation in the range used for cancer therapy and the resulting biological response in a human as well as with the factors that influence this relationship. What is seen in clinical practice is a broad range of doses where the
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Mechanisms and dose-response relationships for radiation-induced cardiovascular disease
Annals of the ICRP, 2012Epidemiological studies have shown a clear association between therapeutic doses of thoracic irradiation and increased risk of cardiovascular disease in long-term cancer survivors. Survivors of Hodgkin's lymphoma and childhood cancers, for example, show 2- to >7-fold increases in risk of cardiac death after total tumour doses of 30–40 Gy, given in 2-
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Dose-response relationship for radiation carcinogenesis in the low-dose region
International Archives of Occupational and Environmental Health, 1994Evidence that low-level radiation substantially enhances the effectiveness of repair mechanisms is summarized. This finding destroys the theoretical basis (there is no other basis) for use of a linear-no threshold dose-response relationship to estimate the cancer risk of exposure to low-level radiation. Such a methodology will exaggerate the risk. This
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Dose-Response Relationship in the Yield of Radiation-Induced Free Radicals in Amino Acids
Physics in Medicine and Biology, 1963The electron spin resonance technique has been used to study the production of long-lived radicals in glycine, alanine, valine, aspartic acid and glutamic acid. The yield of radicals as a function of dose was measured, using as a source of radiation 14·3 MeV electrons at a very high dose rate.
J, ROTBLAT, J A, SIMMONS
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Environmental and Molecular Mutagenesis, 1994
AbstractMicronuclei were assessed among the bone marrow PCEs of mice 28 hr after exposures to 1 to 8 Gy of X‐rays and at 6‐hr intervals from 12‐60 hr after exposures to 2 or 6 Gy. At 28 hr, the frequency of micronuclei declined as the exposure level increased from 1 to 8 Gy.
A F, McFee, S B, Cook, M G, Abbott
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AbstractMicronuclei were assessed among the bone marrow PCEs of mice 28 hr after exposures to 1 to 8 Gy of X‐rays and at 6‐hr intervals from 12‐60 hr after exposures to 2 or 6 Gy. At 28 hr, the frequency of micronuclei declined as the exposure level increased from 1 to 8 Gy.
A F, McFee, S B, Cook, M G, Abbott
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Tests of the Linear, No-threshold Dose-Response Relationship for High-Let Radiation
Health Physics, 1987It is pointed out that induction of lung cancer by exposure to Rn daughters, applied at high doses to miners and at low doses to exposures in homes, provides a very stringent and sensitive test of the linear, no-threshold dose-response relationship for high-LET radiation, because this relationship predicts that a substantial fraction of lung cancer ...
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Journal of Photochemistry and Photobiology B: Biology, 2008
Vitamin D deficiency is a major health concern worldwide. Very little is understood regarding its production in the human body by exposure to UV radiation. In particular, we have no means of predicting how much vitamin D (cholecalciferol) will be produced in the skin after exposure to sunlight.
Olds, William J. +3 more
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Vitamin D deficiency is a major health concern worldwide. Very little is understood regarding its production in the human body by exposure to UV radiation. In particular, we have no means of predicting how much vitamin D (cholecalciferol) will be produced in the skin after exposure to sunlight.
Olds, William J. +3 more
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Health Physics, 2004
Occupational exposures are often recorded as zero when the exposure is below the minimum detection level (BMDL). This can lead to an underestimation of the doses received by individuals and can lead to biased estimates of risk in occupational epidemiologic studies.
Xiaonan, Xue +3 more
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Occupational exposures are often recorded as zero when the exposure is below the minimum detection level (BMDL). This can lead to an underestimation of the doses received by individuals and can lead to biased estimates of risk in occupational epidemiologic studies.
Xiaonan, Xue +3 more
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Experimental Eye Research, 2011
The purpose of this study is to establish the dose response relationship for α-tocopherol protection of ultraviolet radiation (UVR) induced cataract in the rat. Four groups of 20 six-week-old albino Sprague Dawley rats received 5, 25, 50, and 100 IU/day α-tocopherol, whilst another group of 20 rats without any α-tocopherol feeding was the control group.
Jing, Wang +4 more
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The purpose of this study is to establish the dose response relationship for α-tocopherol protection of ultraviolet radiation (UVR) induced cataract in the rat. Four groups of 20 six-week-old albino Sprague Dawley rats received 5, 25, 50, and 100 IU/day α-tocopherol, whilst another group of 20 rats without any α-tocopherol feeding was the control group.
Jing, Wang +4 more
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