A method to adjust radiation dose–response relationships for clinical risk factors
Radiotherapy and Oncology, 2012Several clinical risk factors for radiation induced toxicity have been identified in the literature. Here, we present a method to quantify the effect of clinical risk factors on radiation dose-response curves and apply the method to adjust the dose-response for radiation pneumonitis for patients with/without pre-existing pulmonary co-morbidities.
Ane L Appelt, Ivan R Vogelius
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Dose–Response Relationship for Parathyroid Adenoma after Exposure to Ionizing Radiation in Infancy
Several authors have suggested that there is an excess risk of hyperparathyroidism, adenomas or hyperplasia after exposure to ionizing radiation. There is still, however, some uncertainty about this association, because these diseases are often asymptomatic and escape clinical detection if not specially searched for.
Erik, Holmberg +4 more
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Dose-Response Relationship in Radiation Leukæmia
Nature, 1959A SIGNIFICANT contribution is achieved by Drs. Armitage, Court Brown and Doll in evaluating some models postulated in assessing the leukaemogenic potency of radiations. Along this line, it appears relevant to discuss some possible interpretations of a linear dose-response, observed over a limited range of leukaemia incidence, as evidenced in the study ...
P, ARMITAGE +3 more
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Dose-response relationships for radiation-induced hyperparathyroidism.
The Journal of Clinical Endocrinology & Metabolism, 1995It has been hard to establish with certainty that radiation exposure is a risk factor for developing hyperparathyroidism. In part this is because many cases of hyperparathyroidism remain asymptomatic and escape clinical detection. We present results from a study of 2555 subjects who received external beam radiotherapy to the head and neck area for ...
A B, Schneider +5 more
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Dose–Response Relationship in Radiation Carcinogenesis
Nature, 1961THE question whether the dose–response relationship for neoplasia induced by ionizing radiations is linear or non-linear, and with or without a threshold dose, is one of the most important problems in both basic and applied radiobiology1.
N, ARLEY, R, EKER
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DOSE RESPONSE RELATIONSHIPS FOR ACUTE IONIZING-RADIATION LETHALITY
Health Physics, 2003A review and analysis of the dose response relationship for the probability of acute lethality from prompt or short-term exposure to ionizing radiation is presented. The purpose of this analysis is to provide recommendations concerning estimates of casualties expected from radiation accidents, the use of nuclear weapons, or possible terrorist ...
G H, Anno +3 more
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Ultraviolet radiation, melanocytic naevi and their dose-response relationship
British Journal of Dermatology, 1997Melanocytic naevi on the face and neck of 110 Brisbane secondary school students aged 16-17 years were mapped according to specified regions to investigate the dose-response relationship between ultraviolet (UV) radiation and melanocytic naevi. Highest naevus density occurred in regions receiving a mean UV dose of 0.2-0.4 relative to the vertex while ...
T D, Nguyen +4 more
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THE DOSE‐RESPONSE RELATIONSHIP OF TUMORIGENESIS BY ULTRAVIOLET RADIATION OF 254 nm
Photochemistry and Photobiology, 1988Abstract— Groups of albino hairless mice, Skh‐hrl, were exposed daily to UVC radiation from low pressure Hg arcs (Philips TUV 40W). These lamps emit predominantly radiation of 254 nm. Three groups of animals were used in the experiments, each receiving a different daily dose.The results were described with the Weibull probability function.
Sterenborg, H. J. +2 more
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Dose-Response Relationship in Radiation Therapy of Advanced Carcinoma of the Colon and Rectum
Radiology, 1972Abstract The effectiveness of different courses of treatment of recurrent or metastatic carcinoma of the colon and rectum with radiation therapy was evaluated in terms of nominal-single-dose-equivalent rets (NSDE). The formula for derivation of the NSDE for each treatment course was easly to apply and fitted well with observed clinical data. It appears
P K, Soleimani +2 more
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Influence of Microdosimetric Quantities on Observed Dose-Response Relationships in Radiation Therapy
Radiation Research, 1990The steepness of dose-response curves in radiation therapy depends to a large extent on the statistics of cell killing. This is so if the last few clonogenic tumor cells have to be hit or eradicated by other means to cure the patient. The steepness is dependent on the number of clonogenic cells in the tumor and the possible variation in their ...
L, Lindborg, A, Brahme
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