Results 91 to 100 of about 14,554,987 (328)

Unravelling the impact of linear energy transfer on micronuclei induction from proton and photon irradiation

Scientific Reports
Micronucleus (MN) formation has a strong link to radiation damage and is a common bio-dosimeter for acute radiation exposures. The percentage of cells containing MN (PCMN) has a strong relationship with dose, however variation between previous studies ...
Charlotte J. Heaven, John-William Warmenhoven, Amy L. Chadwick, Elham Santina, Jamie Honeychurch, Christine K. Schmidt, Karen J. Kirkby, Michael J. Merchant, Nicholas T. Henthorn   +8 more
doaj   +1 more source

Protease‐Activated Theranostic Nanomedicine for Endometriosis Treatment

Advanced Functional Materials, EarlyView.
Endometriosis is a chronic gynecological disorder that affects a substantial proportion of reproductive‐aged women. In this study, we identify aberrant overexpression of matrix metalloproteinase‐9 (MMP‐9) in endometriotic lesions and develop a novel multifunctional nanomedicine that integrates MMP‐9‐targeted therapy, ratiometric photoacoustic (PA ...
Panangattukara Prabhakaran Praveen Kumar, Tae Hoon Kim, Hossein Hosseinirad, Maggie Lee, HyeJoo An, Bruce A. Lessey, Daniel Hanavi, Jung‐Ho Shin, Jae‐Wook Jeong, Taeho Kim   +9 more
wiley   +1 more source

Dose-response relationship between tooth loss and risk of stroke.

, 2018
Dose-response relationship between tooth loss and risk of stroke.
Mi Zhang (42795), Xiao Dong (244652), Quan Wang (31224), Haijun Xu (215417), Jiajuan Chen (5029475), Yunjie Wei (5029478), Zhen Gao (609801), Fei Cheng (315348), Fen Qin (4067335)   +8 more
core   +1 more source

Biodegradable Conductors for Implantable and Wearable Transient Bioelectronics

Advanced Functional Materials, EarlyView.
Biodegradable conductors are essential building blocks for transient bioelectronics, enabling temporary sensing, stimulation, and energy transfer while eliminating the need for device retrieval. This review summarizes biodegradable metals, conducting polymers, ionic conductors, and conductive composites, highlighting degradation mechanisms, material ...
Yicheng Zhu, Yijun Liu, Naoji Matsuhisa
wiley   +1 more source

An Evolving New Paradigm for Assessing the Risk of Radiation-Induced Cancer (Radcancer)

Dose-Response
Background The International Commission on Radiological Protection’s system of radiological protection (SRP) is mainly based on the linear no-threshold (LNT) hypothesis for radiation-induced cancer (radcancer).
Bobby R. Scott
doaj   +1 more source

Radiotherapy Dosing for Locally Advanced Non-Small Cell Lung Carcinoma: “MTD” or “ALARA”?

Frontiers in Oncology, 2017
Locally advanced non-small cell lung cancer (LA-NSCLC) is typically treated with thoracic radiotherapy, often in combination with cytotoxic chemotherapy.
Nitin Ohri, Nitin Ohri
doaj   +1 more source

Advancing Human Skin Equivalents: The Crucial Role of Neurovascular Integration

Advanced Healthcare Materials, EarlyView.
This review discusses the importance of integrating vascular and peripheral nerve systems into human skin equivalents (HSEs) to better recapitulate native skin physiology. Recent advances in vascularized, innervated, and neurovascularized HSEs are highlighted, together with emerging bioengineering strategies, current challenges, and future ...
Hao Wu, Lorenzo Moroni, Nicolas Lebonvallet, Vincent Flacher, Paul Wieringa   +4 more
wiley   +1 more source

Radio-Fluorogenic Gel Dosimetry with Coumarin

Bioengineering, 2018
Gel dosimeters are attractive detectors for radiation therapy, with properties similar to biological tissue and the potential to visualize volumetric dose distributions.
Peter A. Sandwall, Brandt P. Bastow, Henry B. Spitz, Howard R. Elson, Michael Lamba, William B. Connick, Henry Fenichel   +6 more
doaj   +1 more source

Chronic gamma-irradiation induces a dose-rate-dependent pro-inflammatory response and associated loss of function in human umbilical vein endothelial cells.

, 2015
A central question in radiation protection research is dose and dose-rate relationship for radiation-induced cardiovascular diseases. The response of endothelial cells to different low dose rates may contribute to help estimate risks for cardiovascular ...
Stefani, J., Haghdoost, S., Ebrahimian, T., Haghdoost, Siamak,, Dublineau, I., Harms-Ringdahl, Mats,, Ebrahimian, T.G., Yentrapalli, R., le Gallic, C., Harms-Ringdahl, M.   +9 more
core   +1 more source

Pressure‐Assisted Drug Delivery Using High‐Pressure Balloon Platform Improves Vascular Drug Penetration and Anti‐Restenotic Effects

Advanced Healthcare Materials, EarlyView.
A dual‐layer high‐pressure drug‐coated balloon (HP@DCB) increased balloon‐wall contact and promoted deeper paclitaxel (PTX) penetration than a conventional noncompliant DCB. In in vivo study, HP@DCB treatment improved luminal patency and reduced neointimal hyperplasia, supporting pressure‐assisted drug delivery as a promising strategy for enhancing the
Seung Jin Eo, So Yun Lim, Dong‐Sung Won, Ji Won Kim, Yubeen Park, Song Hee Kim, Hyemin Lee, Jung‐Min Ahn, Jun‐Kyu Park, Do‐Yoon Kang, Jung‐Hoon Park   +10 more
wiley   +1 more source