Results 221 to 230 of about 260,968 (302)

Enhanced Intracellular Stability and Translation Efficiency of mRNA Drugs by a 2‐arm mRNA Platform

Advanced Science, EarlyView.
We constructed a 2‐arm mRNA, characterized by a unique topology formed through the dimerization of two mRNA 3’ tails. The 2‐arm mRNA improves 3’ tail stability and resistance to nuclease degradation, resulting in an intracellular half‐life of up to 65 h. This method substantially enhances the translation capacity of mRNA drugs.
Xucong Teng, Jiahao Lin, Qiushuang Zhang, Xiangdong Zhang, Yicong Dai, Jinghong Li   +5 more
wiley   +1 more source

Occupational and environmental radiation exposures from small-scale tin ore processing: A case study from Bangka Island. [PDF]

PLoS One
Ishigaki Y, Moritake T, Pradana HA, Eunjoo K, Permana S, Shimazaki K, Hayashi K.   +6 more
europepmc   +1 more source

Selenium‐Based Nanoplatforms: An Emerging Theranostic Paradigm for Gynecological Cancers

Advanced Science, EarlyView.
This reivew summarizes Selenium as a multifunctional anticancer regulator in gynecological cancers. It reduces tumor risk, enhances therapeutic efficacy, and reduces treatment toxicity. Selenium also overcomes chemoraditherapy resistance, improving overall treatment outcomes. ABSTRACT Gynecological cancers present significant therapeutic challenges due
Hejing Liu, Yujia Zhou, Zihan Zhang, Rong Ma, Luyi Ruan, Liqing Miao, Boxin Zhang, Huihui Ji, Tianfeng Chen, Xueqiong Zhu   +9 more
wiley   +1 more source

Mechanistic Effects of Environmental and Medical Low-Dose Radiation Exposure of the Lung. [PDF]

Biomedicines
Puukila S, McEvoy-May J, Hooker AM, Dixon DL.   +3 more
europepmc   +1 more source

Antenna Effect in Halogen‐Containing ZnSm Coordination Compounds: Utilizing Colorimetry for a Room‐Temperature Tunable Ratiometric Molecular Thermometer

Advanced Science, EarlyView.
The ZnSm‐Cl dinuclear molecular complex was synthesized through a simple one‐pot method. ZnL and Sm3+ exhibit complementary temperature‐dependent emission As the temperature increases, a noticeable color difference of ZnSm‐Cl can be observed within the room temperature range of 253‐333 K.
Ye Xia, Yingshan Xue, Feng Pan, Ai Wang, Hong Huang, Zhenxing Li, Bing‐Wu Wang, Song Gao   +7 more
wiley   +1 more source

Microarray-Based Genomic Profiling in Low-Dose Radiation Research: Evidence, Limitations, and Translational Perspectives. [PDF]

Int J Mol Sci
Auganbayeva S, Massabayeva M, Chaizhunussova N, Shabdarbayeva D, Pivina L, Orekhov A, Smailova Z, Apbassova S, Sabitova V, Akhmadiyeva T, Kozhanova S, Mukanova D, Lepesbayev M, Baibussinova A, Lipikhina A, Brait Y, Dyussupov A.   +16 more
europepmc   +1 more source

Quantum Dots for Biomedical Biosensing, NIR‐II Bioimaging, and Phototherapy: Materials Design, Signal Transduction, and Translational Barriers

Advanced Science, EarlyView.
This review outlines bottom‐up and biomimetic fabrication strategies of quantum dots, and highlights their emerging applications in biosensing, multimodal bioimaging, and intelligent cancer theranostics. It further discusses key translational barriers and future perspectives for advancing QD‐based nanomedicine toward clinical implementation.
Jie Ju, Zhifang Liu, Xinran Gao, Wen Sun, Wei Fu, Yanfei Wang   +5 more
wiley   +1 more source

Evaluating the efficacy and immunological impact of combined ICIs and SBRT in HCC: A narrative literature review. [PDF]

Clin Transl Radiat Oncol
Caglayan L, Blanck O, Boda-Heggemann J, Brunner T, Dejonckheere CS, Duda DG, Firat E, Hawkins M, Layer JP, Leitzen C, Mendez Romero A, Niedermann G, Nour Y, Röder F, Sarria GR, Scafa D, Scorsetti M, Wiegreffe S, Grosu AL, Gkika E.   +19 more
europepmc   +1 more source

Non‐Destructive, Reference‐Free Quantitative Analysis of TaOx Memristive Devices Using Soft X‐Ray Radiation

Advanced Electronic Materials, EarlyView.
A non‐destructive, quantitative approach has been developed to explore the nanoscale dynamics of TaOx‐based memristive devices. The utilization of nano‐X‐ray fluorescence analysis enables the direct probing of spatially resolved elemental distributions, including those present in buried layers, that are critical for the resistive switching.
André Wählisch, Xin Zheng, Andreas Haidl, Jan Weser, Christian Stadelhoff, Marc Dummin, Leona J. Bauer, Rainer Unterumsberger, Ilia Valov, Burkhard Beckhoff   +9 more
wiley   +1 more source