Results 121 to 130 of about 11,727,114 (306)

Dose Response Relationship for benzophenones.

open access: yes, 2013
Dose Response Relationship for benzophenones.
Laurence Coiffard (292809)   +3 more
core   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Population pharmacokinetics [PDF]

open access: yesVojnosanitetski Pregled, 2005
Milovanović Jasmina R.   +1 more
doaj   +1 more source

The association between birthweight and adult lung function: insights from the UK Biobank

open access: yesBMC Pulmonary Medicine
Background The potential association between birthweight and adult lung function has been postulated, yet the precise nature of this association in later life remains inconclusive.
Yu Wang   +7 more
doaj   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Dose-response profile (contrast patterns).

open access: yes, 2018
Dose-response profile (contrast patterns).
Tadao Akizawa (316095)   +2 more
core   +1 more source

Dose–Response Relationship Between Aircraft Noise Exposure and Community Annoyance: A Case Study of Hangzhou Xiaoshan International Airport

open access: yesNoise and Health
Objective:With increasing air traffic, aircraft noise pollution near Hangzhou Xiaoshan International Airport has intensified, raising concerns about community annoyance.
Jiakang Lv   +6 more
doaj   +1 more source

Intracoronary Adenosine: Dose-Response Relationship With Hyperemia.

open access: yesJACC. Cardiovascular interventions, 2015
The present study sought to establish the dosage of intracoronary (IC) adenosine associated with minimal side effects and above which no further increase in flow can be expected.Despite the widespread adoption of IC adenosine in clinical practice, no wide-ranging, dose-response study has been conducted.
Adjedj, Julien   +9 more
openaire   +3 more sources

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