Dose-Response Relationship of Phloretin Therapy on Water and Glucose Transport during Experimental Peritoneal Dialysis. [PDF]
Björk M, Martus G, Öberg CM.
europepmc +1 more source
Lack of a Dose‐response Relationship for Carcinogenicity in the Rat Liver with Low Doses of 2‐Amino‐3,8‐dimethylimidazo[4,5‐f]quinoxaline or N‐Nitrosodiethylamine [PDF]
Shoji Fukushima+15 more
openalex +1 more source
Clinical Evidence of the Relationship Between Alanine Aminotransferase and Diabetic Kidney Disease
Yaru Bi,1,* Yang Yang,2,* Xiaojie Yuan,3 Jiping Wang,3 Zhiyuan Liu,4 Suyan Tian,5 Chenglin Sun1,3 1Department of Endocrinology and Metabolism, First Hospital of Jilin University, Changchun, 130000, People’s Republic of China; 2Department of ...
Bi Y+6 more
doaj
Objectives There is growing interest in evaluating new strategies to delay or prevent post‐traumatic osteoarthritis (PTOA) in individuals who have sustained anterior cruciate ligament (ACL) injury. This study sought to determine characteristics of potential treatments that are acceptable to patients with ACL injury.
Kevin Kennedy+9 more
wiley +1 more source
Exploring the Dose-Response Relationship Between Nature-Based Outdoor Activities, Nature Connectedness and Social Health In Adolescents: A Quasi-Experimental Controlled Study. [PDF]
Choe EY, Lee JY, Zhu S.
europepmc +1 more source
Defining hormesis: the necessary tool to clarify experimentally the low dose–response relationship [PDF]
G Carelli, Ivo Iavicoli
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β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio+11 more
wiley +1 more source
First evidence of a biomarker-based dose-response relationship in chronic pain using physiological closed-loop spinal cord stimulation. [PDF]
Muller L+6 more
europepmc +1 more source
The prodrug strategy used in this study offers new promise for cancer metabolism‐based therapies. JHU083, a prodrug that, when cleaved by protease in the tumor microenvironment, yields the glutamine antagonist DON. JHU083 inhibits tumor growth by targeting glutamine‐addicted cancer cells and suppressing glutamine‐dependent M2 macrophages, leading to a ...
Tianhe Li+10 more
wiley +1 more source
The dose-response relationship and gender differences of serum uric acid with total cholesterol: a cross-sectional study. [PDF]
Guo L, Cai L, Hu L, Zhou Y.
europepmc +1 more source