Dose-response relationship between different physical activity types and depressive symptoms in middle-aged and elderly people: a study of Chinese urban-rural differences. [PDF]
Wang R+7 more
europepmc +1 more source
As many patients with inflammatory arthritis (IA) have chronic pain, understanding how to best assess and manage pain in IA is a priority. Comorbid depression is prevalent in adults with IA, affecting 15% to 39% of people. Although pain and depression are thought to be associated in IA, this concept is largely based on cross‐sectional data.
Natasha Cox+3 more
wiley +1 more source
Lack of a Dose‐response Relationship for Carcinogenicity in the Rat Liver with Low Doses of 2‐Amino‐3,8‐dimethylimidazo[4,5‐f]quinoxaline or N‐Nitrosodiethylamine [PDF]
Shoji Fukushima+15 more
openalex +1 more source
Dose-response relationship between sedentary time and anxiety and the moderating effect of a 10-min walk: a cross-sectional study. [PDF]
Tian Z+5 more
europepmc +1 more source
Metabolic Consequences of Rheumatoid Arthritis
Patients with rheumatoid arthritis (RA) may have metabolic disruption, which can contribute to adverse long‐term outcomes, for multiple reasons. Patients with RA appear to have a higher risk of sarcopenia, type 1 and type 2 diabetes mellitus, metabolic syndrome, and hypertension. Systemic inflammation in RA can cause a “lipid paradox,” with reduced low‐
Stevie Barry+2 more
wiley +1 more source
Dose–response relationships: an overview, a generative model and its application to the verification of descriptive models [PDF]
M.A. Murado+2 more
openalex +1 more source
Changes in lactate concentration are accompanied by opposite changes in the pattern of fat oxidation: Dose-response relationship. [PDF]
Benítez-Muñoz JA+6 more
europepmc +1 more source
Ageism in Rheumatology: the Healthcare Professional's Perspective
Objective Ageism (age‐based stereotypes, prejudice, or discrimination) is prevalent and linked to prolonged disability and reduced lifespan in older adults. Little is known about ageism within rheumatology. This study explores the healthcare professional's (HCP) perception of the care of older adults and how ageist attitudes or perspectives may impact ...
Aaron P. Smith+4 more
wiley +1 more source
Fludrocortisone dose-response relationship in septic shock: a randomised phase II trial. [PDF]
Walsham J+24 more
europepmc +1 more source
Whole‐Blood RNA Sequencing Profiling of Patients With Rheumatoid Arthritis Treated With Tofacitinib
Objective Patients with rheumatoid arthritis (RA) often fail to respond to therapies, including JAK inhibitors (JAKi), and treatment allocation is made via a trial‐and‐error strategy. A comprehensive analysis of responses to JAKi, including tofacitinib, by RNA sequencing (RNAseq) would allow the discovery of transcriptomic markers with a two‐fold ...
Chiara Bellocchi+11 more
wiley +1 more source