Optimal experimental design for cytogenetic dose–response calibration curves [PDF]
International Journal of Radiation Biology, 2020 Purpose: To introduce optimal experimental design techniques in the cytogenetic biological dosimetry practice. This includes the development of a new optimality criterion for the calibration of radiation doses.Materials and methods: The most typical optimal design criterion and the one developed in this research are introduced and applied in an example
Manuel Higueras +2 more
openaire +4 more sources
Регуляторные исследования и экспертиза лекарственных средств, 2022 Pharmacokinetic parameters are important for calculating the absorbed dose; they also provide an indirect measure of the in vivo stability of a radiopharmaceutical.
E. D. Stepchenkova +9 more
doaj +1 more source
Determination of itraconazole and hydroxyitraconazole in plasma by use of liquid chromatography-tandem mass spectrometry with on-line solid-phase extraction [PDF]
, 2003 In this paper a method for the simultaneous quantification of the anti-fungal drug itraconazole and its co-active metabolite hydroxyitraconazole in plasma employing liquid chromatography tandem-mass spectrometry and automated solid-phase extraction is ...
Schiel, Xaver +2 more
core +1 more source
Radiolabeling Technique of Silver Nanoparticles (AgNPs) with Iodine-131 Radionuclide
Atom Indonesia, 2020 Radiotherapy is an effective cancer therapy, where a certain dose of radiation is aimed specifically at target and is unaffecting to normal tissue. A selectiveradionuclide must be attached to the specific targeted organ.
U.N. Sholikhah +5 more
doaj +1 more source
Serum Concentrations of Myostatin and Myostatin-Interacting Proteins do not differ between young and Scarcopenic elderly men [PDF]
, 2011 Peer ...
A. DeVries +41 more
core +1 more source
A selective alpha1D-adrenoreceptor antagonist inhibits human prostate cancer cell proliferation and motility "in vitro" [PDF]
, 2016 The progression of prostate cancer (PC) to a metastatic hormone refractory disease is the major contributor to the overall cancer mortality in men, mainly because the conventional therapies are generally ineffective at this stage. Thus, other therapeutic
Bolchi, Cristiano +8 more
core +2 more sources
Placental DEPTOR as a stress sensor during pregnancy [PDF]
, 2011 The author(s) has paid for this article to be freely available under the terms of the Creative Commons Attribution Non-Commercial Licence (http://creativecommons.org/licenses/by-nc/2.5/) which permits unrestricted non-commercial use, distribution and ...
Gidron, Y +4 more
core +2 more sources
Preclinical Analysis of JAA-F11, a Specific Anti-Thomsen-Friedenreich Antibody via Immunohistochemistry and In Vivo Imaging. [PDF]
, 2018 The tumor specificity of JAA-F11, a novel monoclonal antibody specific for the Thomsen-Friedenreich cancer antigen (TF-Ag-alpha linked), has been comprehensively studied by in vitro immunohistochemical (IHC) staining of human tumor and normal tissue ...
Adams, Julia +13 more
core +2 more sources
Impact of glucuronide interferences on therapeutic drug monitoring of posaconazole by tandem mass spectrometry [PDF]
, 2010 Background: Posaconazole is a novel antifungal drug for oral application intended especially for therapy of invasive mycoses. Due to variable gastrointestinal absorption, adverse side effects, and suspected drug-drug interactions, therapeutic drug ...
Burghardt, Stephan +4 more
core +1 more source
EJNMMI Physics, 2023 Purpose A strategy for management of radioactive waste associated with 177Lu-dotatate (Lutathera®) treatments was established in our institution, based on predicted storage times of 3–5 years extrapolated from the results of a 2-year measurement study ...
Sylviane Prevot +6 more
doaj +1 more source