Results 231 to 240 of about 233,485 (260)

Dose-dependent pharmacokinetics and cancer chemotherapy

Cancer Chemotherapy and Pharmacology, 1981
Dose-dependent pharmacokinetics have been reported more frequently for anticancer drugs than for other drugs, probably because anticancer drugs are studied over a wide range of doses during early evaluation and because of the increasing use of anticancer drugs at very high doses.
G, Powis, M M, Ames, J S, Kovach
openaire   +2 more sources

Non-monotonic dose dependence of thermoluminescence

Radiation Protection Dosimetry, 2006
The thermoluminescence (TL) intensity in different materials is usually a monotonic increasing function of the dose, which quite often reaches a saturation value. In several materials, however, non-monotonic dose dependence has been observed. The TL intensity reached a maximum at a certain dose and decreased at higher ones.
R, Chen, D, Lo, J L, Lawless
openaire   +2 more sources

Dose-dependent pharmacokinetics of cimetidine in the rat

Xenobiotica, 1987
The pharmacokinetics of cimetidine were studied in the rat after intraperitoneal administration of 10, 40 and 100 mg/kg. The area under the plasma concentration-time curve increased more than proportionately with dose. The total plasma clearance of cimetidine decreased as the dose increased (4.11 to 2.21 l/h per kg) with a consequent increase in half ...
A, Adedoyin, L, Aarons, J B, Houston
openaire   +2 more sources

Dose-Dependence of the Nifedipine/Digoxin Interaction?

1986
The dose-dependence of the nifedipine/digoxin interaction was investigated in seven healthy volunteers. After an adequate loading dose of digoxin for two weeks, 0.25 mg digoxin was given alone orally twice daily. Afterwards, 0.25 mg digoxin was administered twice daily for three one week periods combined with capsules of nifedipine 5 mg, 10 mg or 20 mg
H J, Hutt, W, Kirch, P, Dylewicz, E E, Ohnhaus   +3 more
openaire   +2 more sources

Dose-dependent pharmacokinetics

Pharmacology & Therapeutics, 1983
J M, van Rossum, G, van Lingen, J P, Burgers   +2 more
openaire   +2 more sources

Dosing Time-Dependent Actions of Psychostimulants

2009
The concept of the dosing time-dependent (DTD) actions of drugs has been used to describe the effects of diurnal rhythms on pharmacological responsiveness. Notwithstanding the importance of diurnal variability in drug pharmacokinetics and bioavailability, it appears that in the central nervous system (CNS), the DTD actions of psychotropic drugs involve
H, Manev, T, Uz
openaire   +2 more sources

A case of dose-dependent Heiner syndrome

The Journal of Allergy and Clinical Immunology: In Practice, 2023
Gabrielle, Robertson, Brian, Goodman, Rachana, Choksi, Zoya, Treyster   +3 more
openaire   +2 more sources

Dose rate and SDD dependence of commercially available diode detectors

Medical Physics, 2004
Timothy Zhu
exaly  

Weak energy dependence of EBT gafchromic film dose response in the 50kVp–10MVp X-ray range

Applied Radiation and Isotopes, 2006
Peter K N Yu, Tsang Cheung, Martin J Butson   +2 more
exaly  

Efficacy, tolerability, and safety of low-dose and high-dose baclofen in the treatment of alcohol dependence: A systematic review and meta-analysis

European Neuropsychopharmacology, 2018
, Arjen Sutterland, Kirsten Morley
exaly