Results 71 to 80 of about 585,390 (295)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

The Evaluation of Dose Enhancement within Gold Nanoparticle Radio-Sensitized Tumor Using Proton Therapy

مجله دانشکده پزشکی اصفهان, 2017
Background: Because of its radio-biological and physical advantages, proton therapy method is highly popular compared to other radiotherapy methods.
Somayeh Malmir, Ali Asghar Molavi, Saeed Mohammadi   +2 more
doaj  

Total-liver-volume perfusion CT using 3-D image fusion to improve detection and characterization of liver metastases [PDF]

, 2008
The purpose of this study was to evaluate the feasibility of a totalliver- volume perfusion CT (CTP) technique for the detection and characterization of livermetastases.
Kuijk, Cornelis van, Meijer, Sybren, Meijerink, Martijn, Tol, Petrousjka van den, Waesberghe, Jan van, Weide, Lineke van der   +5 more
core   +3 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Radiobiological perspective on metrics for quantifying dose enhancement effects of High-Z nanoparticles

Frontiers in Nanotechnology
High atomic number (high-Z) metal nanoparticles (NPs) have emerged as transformative radiosensitizers in cancer radiotherapy, offering the potential to amplify tumor-specific radiation effects while sparing healthy tissues.
Yan Luo
doaj   +1 more source

Modification of intergrain connectivity, upper critical field anisotropy, and critical current density in ion irradiated MgB2 films

, 2005
We study the effect of 100 MeV Silicon and 200 MeV Gold ion irradiation on the inter and intra grain properties of superconducting thin films of Magnesium Diboride.
Bean, Bouquet, Braccini, Bu, C.B. Eom, Canfield, Chikumoto, Choi, D.M. Kim, Dou, Ferrando, Gandikota, Gerhäuser, Giubileo, Gurevich, Gurevich, Iavarone, J.E. Giencke, Liu, Mazin, Okayasu, P.K. Mishra, Patnaik, Putti, Putti, Ravi Kumar, Rowell, S. Patnaik, S.D. Kaushik, Shinde, Szabo, Ziegler   +31 more
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Mathematical modeling predicts enhanced growth of X-ray irradiated pigmented fungi. [PDF]

PLoS ONE, 2014
Ionizing radiation is known for its cytotoxic and mutagenic properties. However, recent evidence suggests that chronic sub-lethal irradiation stimulates the growth of melanin-pigmented (melanized) fungi, supporting the hypothesis that interactions ...
Igor Shuryak, Ruth A Bryan, Joshua D Nosanchuk, Ekaterina Dadachova   +3 more
doaj   +1 more source

Assessing the motivational effects of ethanol in mice using a discrete-trial current-intensity intracranial self-stimulation procedure. [PDF]

, 2020
BackgroundAlcohol (ethanol) produces both rewarding and aversive effects, and sensitivity to these effects is associated with risk for an alcohol use disorder (AUD).
Barkley-Levenson, Amanda M, Der-Avakian, Andre, Palmer, Abraham A   +2 more
core  

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source