Results 81 to 90 of about 345,855 (252)

Nanoparticle-Mediated Radiotherapy: Unraveling Dose Enhancement and Apoptotic Responses in Cancer and Normal Cell Lines. [PDF]

Biomolecules, 2023
Kouri MA, Spyratou E, Kalkou ME, Patatoukas G, Angelopoulou E, Tremi I, Havaki S, Gorgoulis VG, Kouloulias V, Platoni K, Efstathopoulos EP.   +10 more
europepmc   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

A Monte Carlo Study on the Effect of Various Neutron Capturers on Dose Distribution in Brachytherapy with 252Cf Source

Journal of Biomedical Physics and Engineering, 2017
Background: In neutron interaction with matter and reduction of neutron energy due to multiple scatterings to the thermal energy range, increasing the probability of thermal neutron capture by neutron captures makes dose enhancement in the tumors ...
Firoozabadi M. M., Izadi Vasafi Gh., karimi-sh K., Ghorbani M.   +3 more
doaj  

Estimation of dose enhancement to soft tissue due to backscatter radiation near metal interfaces during head and neck radiothearpy - A phantom dosimetric study with radiochromic film

Journal of Medical Physics, 2014
The objective of this study was to investigate the dose enhancement to soft tissue due to backscatter radiation near metal interfaces during head and neck radiotherapy.
Rajesh Ashok Kinhikar, Chandrashekhar M Tambe, Kalpana Patil, Mahadev Mandavkar, Deepak D Deshpande, Rajendra Gujjalanavar, Prabha Yadav, Ashwini Budrukkar   +7 more
doaj   +1 more source

A review of bismuth-based nanoparticles and their applications in radiosensitising and dose enhancement for cancer radiation therapy. [PDF]

IET Nanobiotechnol, 2023
Shahbazi-Gahrouei D, Choghazardi Y, Kazemzadeh A, Naseri P, Shahbazi-Gahrouei S.   +4 more
europepmc   +1 more source

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

FEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés, Luise Franz, Christian P.R. Hackenberger   +2 more
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Monte Carlo study on nanogold dose enhancement for breast radiotherapy using an ICRP female computational phantom

Journal of Taibah University for Science
Due to distinct photoelectric absorption properties and physiochemical features, high-atomic-element nanomaterials are frequently used as radiosensitizer for radiotherapy, such as gold nanoparticles.
Turki Almatani, Wafa M. Al-Saleh
doaj   +1 more source

Catalytic activity imperative for nanoparticle dose enhancement in photon and proton therapy. [PDF]

Nat Commun, 2022
Gerken LRH, Gogos A, Starsich FHL, David H, Gerdes ME, Schiefer H, Psoroulas S, Meer D, Plasswilm L, Weber DC, Herrmann IK.   +10 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source