Results 81 to 90 of about 685,461 (196)

Ultrasound‐Responsive Piezoelectric Fibrous Membrane Promotes Neurological Recovery After TBI by Modulating Microglial Polarization via Restoring Mitochondrial Dynamic Homeostasis

Advanced Science, EarlyView.
We demonstrate a novel therapy for traumatic brain injury TBI using a LIPUS‐responsive Piezoelectric fibrous membrane. It targets microglial mitochondria via in situ electrical signals, restoring homeostasis and reducing oxidative stress to promote an anti‐inflammatory M2 phenotype.
Wei Li, Runzhe Huang, Qingyuan Wu, Pengbo Zhou, Dangli Ren, Jingjing Wang, Hanjie Niu, Zemeng Li, Hongtao Sun, Huiyu Liu   +9 more
wiley   +1 more source

Dot-ELISA no diagnóstico da neurocisticercose

, 2004
The aim of the present study was to standardize and evaluate dot-Enzyme linked immunosorbent assay (Dot-ELISA), a simple and rapid test for the detection of cysticercus antibodies in the serum for the diagnosis of neurocysticercosis (NCC).
Parija, S.C., Biswas, Rakhi, Narayan, S.K.   +2 more
core  

In Situ Stress‐Dispersing Hydrogel Millispheres via Load Redistribution to Restore Nucleus Pulposus Metabolic Homeostasis

Advanced Science, EarlyView.
Local stress concentration disrupts metabolic homeostasis and induces inflammation in the nucleus pulposus (NP), thereby accelerating intervertebral disc degeneration (IDD). A biomimetic HA/ChS hydrogel millimeter sphere (ChS@HM) is developed to enable synergistic stress dispersion and sustained hydration lubrication.
Ang Li, Hui Yuan, Honglei Xiao, Xiaodong Liu, Wenguo Cui   +4 more
wiley   +1 more source

Highly Sensitive and Specific Monoclonal Antibody-Based Serological Methods for Rice Ragged Stunt Virus Detection in Rice Plants and Rice Brown Planthopper Vectors

Journal of Integrative Agriculture, 2014
Rice ragged stunt virus (RRSV) is a serious rice disease in Asia, causing serious yield losses on rice. The capsid protein (CP) gene of the major outer capsid protein of RRSV was expressed in Escherichia coli BL21 (DE3) using the pMAL-C2X expression ...
Huan LIU, Xi-jiao SONG, Yue-qun NI, Li-na LU, Xue-ping ZHOU, Jian-xiang WU   +5 more
doaj   +1 more source

Dot-ELISA for the diagnosis of neurocysticercosis

, 2004
O objetivo do presente estudo foi estandardizar e avaliar o Dot-ELISA, um teste simples e rápido para detectar anticorpos de cisticercos no soro para diagnóstico da neurocisticercose (NCC).
Parija, S.C., Biswas, Rakhi, Narayan, S.K.   +2 more
core  

Single‐Cell RNA Editing Identifies T Cell ADAR1 as a Key Regulator of Immune Exhaustion and Anti‐PD‐1 Resistance in Colorectal Cancer

Advanced Science, EarlyView.
Single‐cell RNA editing analysis identifies ADAR1 as a regulator of dysfunctional T cell states in colorectal cancer. Elevated ADAR1 activity promotes T cell exhaustion and impairs antitumor immunity partly through TGF‐β‐SMAD signaling, contributing to anti‐PD‐1 resistance and highlighting T cell ADAR1 as a potential therapeutic target and biomarker ...
Da Kang, Song‐Zuo Xie, Yong‐Zhou Luo, Xin‐Pei Deng, Xi‐Rong Tan, Ze‐Geng Chen, Ling‐Xing Zeng, Gong Chen, Pei‐Rong Ding, Zhi‐Zhong Pan, Rong‐Xin Zhang   +10 more
wiley   +1 more source

Development, optimization, and validation of an in-house Dot-ELISA rapid test based on SAG1 and GRA7 proteins for serological detection of Toxoplasma gondii infections

Infection and Drug Resistance, 2019
Aref Teimouri,1,2 Mohammad Hossein Modarressi,3 Saeedeh Shojaee,1 Mehdi Mohebali,1,4 Mostafa Rezaian,1 Hossein Keshavarz1,41Department of Medical Parasitology and Mycology, Tehran University of Medical Sciences, Tehran, Iran; 2Students Scientific ...
Teimouri A, Modarressi MH, Shojaee S, Mohebali M, Rezaian M, Keshavarz H   +5 more
doaj  

Measles serodiagnosis: standardization and evaluation of a dot-ELISA

, 1994
A técnica de Dot-ELISA (DE) para detecção de anticorpos IgM e IgG anti vírus do sarampo foi padronizada e avaliada utilizando-se antígeno viral obtido por tratamento com desoxicolato de sódio (DOC). Foram estudadas 192 amostras de soros, compreendendo 47
Ferreira, Antonio W., Sumita, Laura M., Souza, Vanda A. U. F. de, Andrade Junior, Heitor F., Vaz de Lima, Lourdes R. A., Hoshino-Shimizu, Sumie, Pannuti, Claudio S.   +6 more
core  

Nanomaterials for Allergy Diagnosis and Treatment: Advances, Opportunities and Translational Challenges

Advanced Science, EarlyView.
Nanomaterials offer dual applications in allergy management. For diagnosis, nanomaterials enhance analytical sensitivity and improve detection in specific IgE and functional assays such as the basophil activation test (BAT). For allergen‐specific immunotherapy, nanomaterials enable allergen masking and controlled release, and effectively modulate the ...
Madiha Habib, Shan Jiang, Joyce ZX Lee, CW Lim, HL Yeung, Nicki YH Leung, Patrick SC Leung, Ting F Leung, Christine YY Wai   +8 more
wiley   +1 more source

Dot enzyme-linked immunosorbent assay (dot-ELISA) for schistosomiasis diagnosis using dacron as solid-phase

Revista da Sociedade Brasileira de Medicina Tropical, 1999
Dacron and nitrocellulose were evaluated as matrices for the dot enzyme linked immunosorbent assay (dot-ELISA) for schistosomiasis and compared to indirect immunofluorescence (IMF).
Silvia Maria Lucena Montenegro, Joanne D'arc Bezerra da Silva, Maria Edileuza Felinto de Brito, Luiz Bezerra de Carvalho Junior   +3 more
doaj