Results 61 to 70 of about 97,738 (248)

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Information Processing Biases and Attachment Styles in Adolescents with Dissociative Disorders

Indian Journal of Psychological Medicine
Background: Dissociative disorders invade and interfere with the person’s continuity of normal psychological functioning and exhibit slower or impaired processing of threat-related information and attachment styles play a significant role in their ...
Ritwika Nag, Nishant Goyal, Madhumita Bhattacharyya   +2 more
doaj   +1 more source

Audiovisual Modulation of Attention Towards Fearful Stimuli

i-Perception, 2011
Earlier research has shown that, in a dot-probe experiment, simultaneously presented vocal utterances (one with emotional prosody, one neutral) showed faster responses to probes replacing the location of emotional prosody, indicating a cross-modal ...
Martijn Balsters, Emiel Krahmer, Marc Swerts, Ad Vingerhoets   +3 more
doaj   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Voltage-controlled two-dimensional Fresnel diffraction pattern in quantum dot molecules

Scientific Reports
This study explores the influence of inter-dot tunneling effects within a quantum dot molecule on the Fresnel diffraction phenomenon. Our findings indicate that the Fresnel diffraction of the output probe Gaussian field can be manipulated by adjusting ...
Hamed Mehrabzadeh, Hamid Khoshdel, Mohammad Mahmoudi, Zahra Amini Sabegh, Saifollah Rasouli   +4 more
doaj   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Is It Possible to Train the Focus on Positive and Negative Parts of One’s Own Body? A Pilot Randomized Controlled Study on Attentional Bias Modification Training

Frontiers in Psychology, 2019
Dysfunctional body- and shape-related attentional biases are involved in the etiology and maintenance of eating disorders (ED). Various studies suggest that women, particularly those with ED diagnoses, focus on negatively evaluated parts of their own ...
Nicole Engel, Manuel Waldorf, Andrea Hartmann, Anna Voßbeck-Elsebusch, Anna Voßbeck-Elsebusch, Silja Vocks   +5 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Refractive index change in a double quantum dot structure

Results in Optics
The density matrix theory models the refractive index change in a double quantum dot (DQD) system. The orthogonalized plane wave (OPW) is considered for wetting layer (WL)-quantum dot (QD) transitions, and the transition momenta are calculated.
Suha Hadi, Mohammed A.A. Abbas, Faten K. Hachim, Baqer Obaid Al-Nashy, Amin H. Al‑Khursan   +4 more
doaj   +1 more source