Results 101 to 110 of about 727,918 (197)

Fine mapping of epitopes on IBDV VP4 protein with peptide ELISA and peptide dot-ELISA.

, 2015
(A) Eleven BSA-conjugated peptides (spanning residues 515–558, 550–565, 563–600, 598–631, 618–641, 638–662, 653–674, 680–706, 700–717, 713–741 and 720–750) were coated on a 96-well plate in the peptide ELISA or dotted on a nitrocellulose membrane in the ...
Boli Hu (750407), Lu Jia (295253), Jiyong Zhou (507690), Weiying Si (750408), Sanying Wang (507688), Xiaojuan Zheng (750409)   +5 more
core   +1 more source

Inorganic Nanomaterials can Promote or Inhibit Tumor Metastasis Depending on Tumor Microenvironment Composition

Advanced Science, EarlyView.
As engineered nanomaterials gain prominence in cancer imaging and therapy, understanding their impact on tumor progression becomes increasingly critical. We demonstrate that gold and silica‐coated gold nanomaterials can either suppress or enhance breast cancer metastasis through distinct tumor microenvironment interactions, while identifying ...
Kiana Buttiens, Xiaoqi Zheng, Xueqi Fan, Mukaddes Izci, Christy Maksoudian, Irati Perez Gilabert, Tianjiao Chu, Filipa Goncalves, Jonas Dehairs, Johan Swinnen, Bella B. Manshian, Stefaan J. Soenen   +11 more
wiley   +1 more source

Measles serodiagnosis: standardization and evaluation of a dot-ELISA

, 1994
A técnica de Dot-ELISA (DE) para detecção de anticorpos IgM e IgG anti vírus do sarampo foi padronizada e avaliada utilizando-se antígeno viral obtido por tratamento com desoxicolato de sódio (DOC). Foram estudadas 192 amostras de soros, compreendendo 47
Ferreira, Antonio W., Sumita, Laura M., Souza, Vanda A. U. F. de, Andrade Junior, Heitor F., Vaz de Lima, Lourdes R. A., Hoshino-Shimizu, Sumie, Pannuti, Claudio S.   +6 more
core  

Nano Proton Scavengers Modulate Endosomal pH to Inhibit Microglial Activation and Enhance Stroke Recovery

Advanced Science, EarlyView.
Amphiphilic sulfonated chitosan nanoparticles buffer endo/lysosomal acidity in microglia by limiting V‐ATPase membrane recruitment and restoring endosomal homeostasis. Following systemic administration, they accumulate in the ischemic hemisphere partly through association with infiltrating immune cells, suppress TLR3/IRF3 and TLR4/NF‐κB signaling ...
Xuanlin Wang, Yujing Shi, Zehua Gao, Jing Wang, Changsheng Liu   +4 more
wiley   +1 more source

One‐Step Immobilized Phage Depolymerase Coatings for Catheter‐Related Bloodstream Infections

Advanced Science, EarlyView.
Catheter‐related bloodstream infections (CRBSI) caused by drug‐resistant Gram‐negative bacteria remain a major clinical challenge. Here, a polydopamine‐assisted depolymerase coating degrades bacterial capsules and restores serum‐mediated killing, effectively suppressing biofilms and reducing bacterial burden in vitro, ex vivo, and in vivo, presenting a
Lingkai Dong, Xingjin Li, Tao Hu, Qianqian Lu, Xiaoxu Zhang, Xi Chen, Yifan Luo, Zhong Zuo, Ronald Man Yeung Wong, Miao Xu, Tiancong Zhao, Sharon Shui Yee Leung   +11 more
wiley   +1 more source

Defect‐Engineered BiO2‐X Nanosheets Mediate Sono‐Thermomechanical ECM Remodeling for Hepatocellular Carcinoma Immunotherapy

Advanced Science, EarlyView.
Herein, an ultrasound‐responsive BiO2‐X/siFn1 nanoplatform is developed to overcome anti‐PD‐1 resistance in hepatocellular carcinoma. Upon ultrasound irradiation, the platform downregulates fibronectin expression, while its sonothermal effect softens the dense extracellular matrix and activates antitumor immunity in the tumor microenvironment, thereby ...
Huimin Tian, Shen Zhang, Bolin Wu, Yichi Chen, Haitao Shang, Haoyan Tan, Chunyue Wang, Weichen Xu, Huixiong Xu, Haohao Yin, Wen Cheng   +10 more
wiley   +1 more source

Development of ELISA and Dot-ELISA systems for the rapid diagnosis of bovine rotavirus infections

, 2010
En önemli viral gastroenterit etkenlerinden BRV, sığırlarda ekonomik kayıplara neden olan dünya üzerinde yaygın bir viral etkendir bu nedenle yenidoğan buzağı yaşamının ilk gününden itibaren hızlı test tekniklerinin uygulanması önemlidir.
Yanbakan, Serpil
core  

Autophagy Orchestrates Anti‐Tumor Immunity to Enhance Chemosensitivity via the FBXW2/C/EBPβ/TIMP‐2 Axis in Colorectal Cancer

Advanced Science, EarlyView.
Chemotherapy leverages tumor‐cell autophagy to reshape the colorectal cancer immune microenvironment. Autophagy degrades FBXW2 to promote C/EBPβ‐mediated TIMP‐2 transcription and MMP‐9 suppression, driving intra‐tumoral CD8+ T‐cell infiltration. Targeting MMP‐2/9 or restoring TIMP‐2 overcomes chemo‐resistance in autophagy‐deficient tumors. ABSTRACT The
Bing Cheng, Chaoying Wei, Zhitong Niu, Jinxin Chen, Guojie Long, Yingzhen Weng, Qiufeng Liu, Yue Jiang, Panpan Wang, Ronghua Zhang, Qiang Yu, Xiaojian Wu, Wenyu Wang   +12 more
wiley   +1 more source

Intrasplenic Thymus Organogenesis from Injectable Tissue Fragments Restores Functional T‐Cell Immunity

Advanced Science, EarlyView.
Clinical intramuscular thymus transplantation yields only short‐lived efficacy and marginal therapeutic benefits. Benefiting from the spleen's intrinsic strengths—rapid vascular perfusion, abundant developmental factors, and resident progenitors—the intrasplenic thymic grafts achieve robust thymic regeneration and substantial T‐cell reconstitution ...
Shaocong Wang, Zijian Zhang, Fulin Dai, Zhijie Yin, Zhen Xing, Yurong Li, Haochong Lei, Junfeng Zhang, Chunyan Liu, Yan Li, Lei Dong   +10 more
wiley   +1 more source

Use of Nickel Chloride in Dot-ELISA for Detection of Haemonchus sp. Infection in Sheep [PDF]

, 2015
Haemonchosis is a major cause of production losses in livestock, particularly sheep and goat. In this study, Nickel chloride is used in dot-ELISA for the detection of infection in sheep, experimentally-infected with 10,000 L 3 Haemonchus contortus. Serum
Bharati, Priyank, J.M. Kataria, Arvind Prasad   +1 more
core