Results 111 to 120 of about 727,918 (197)

Evaluation of Newly Developed Dot-ELISA Test for Identification of Naja-naja sumantrana and Calloselasma rhodostoma Venom Antigens

, 2012
Snake bite cases in Malaysia most often involve the species Naja-naja and Calloselasma rhodostoma. In keeping with the need for a rapid snake venom detection kit in a clinical setting, plate and dot-ELISA test for the venoms of Naja-naja sumatrana ...
T .H. Wong, S. Ambu, A.S. Sikarwar
core   +1 more source

KLF5 Downregulation Links Impaired BNIP3‐Mediated Mitophagy to Inflammatory Valve Remodeling in Calcific Aortic Valve Disease

Advanced Science, EarlyView.
In human CAVD, KLF5 is reduced in VIC‐rich regions and remodeling/stress‐associated VIC states. In VICs, KLF5 sustains BNIP3 promoter activity and BNIP3‐mediated mitophagy, thereby limiting cytosolic mtDNA accumulation. KLF5 loss weakens mitochondrial quality control and enhances mtDNA‐sensitive STING/NF‐κB/NLRP3 inflammatory signaling under osteogenic
Jin‐Hui Bian, Jia‐Xi Gu, Zhang Yue, Chun‐Ze Yuan, Hai‐Bin Ji, Ao Li, Yu Zhong, Xiu‐Fan Xu, Yu‐Qiu He, Ye‐Fan Jiang, Hong‐Shan Chen, Xiang Chen, Meng‐Lin Chao, Yong‐Feng Shao   +13 more
wiley   +1 more source

Koyunlarda corynebacterium pseudotuberculosis'in ELISA ve dot-blot ELISA ile teşhisi

, 2001
Koyunlarda Corynebacterium pseudotuberculosis' in ELISA ve Dot-blot ELISA ile Teşhisi Bu çalışmada, koyun kan serumlarında C. pseudotuberculosis antikorlarının saptanması için; ekzotoksin ELISA, sonike ELISA ve dot-blot ELISA teknikleri standardize ...
İlhan, Ziya
core  

Desenvolvimento e padronização do DOT-ELISA para o diagnóstico sorológico da MAEDI-VISNA. [PDF]

, 2017
Resumo: A Maedi Visna é uma enfermidade típica de ovinos, embora possa infectar, também, caprinos. Encontra-se disseminada em todo mundo, exceto na Austrália e Nova Zelândia. No Brasil, é sabida a existência de rebanhos infectados inclusive no Ceará, mas
ARAGÃO, M. A. do C.
core  

A Photothermally Amplified Enzyme–Nitric Oxide Co‐Regulatory System Reprograms Pathological ECM–Fibroblast Crosstalk to Alleviate Hypertrophic Scarring

Advanced Science, EarlyView.
An enzyme–nitric oxide (NO) co‐regulatory strategy reprograms pathological extracellular matrix (ECM)–fibroblast crosstalk in hypertrophic scars. Enzymatic degradation of pre‐existing ECM relieves aberrant mechanical cues, while NO‐mediated fibroblast phenotypic modulation restrains excessive collagen synthesis.
Junzhe Fu, Fan Jia, Yixian Mu, Wanzhe Liu, Dingqi Tang, Qiao Jin, Jian Ji, Youxiang Wang   +7 more
wiley   +1 more source

Macrophage PARP7 Alleviates Septic Cardiomyopathy by Interacting With TBK1 and Suppressing TBK1‐Driven Inflammatory Response

Advanced Science, EarlyView.
In septic cardiomyopathy, PARP7 directly binds TBK1 and mediates its ADP‐ribosylation, thereby repressing TBK1‐driven proinflammatory signaling in macrophages. ABSTRACT Septic cardiomyopathy is a life‐threatening complication of sepsis, and an uncontrolled inflammatory response represents a key pathogenic mechanism. PARP7 negatively regulates the IFN‐I
Jibo Han, Lintao Wang, Xin Zhong, Shenggang Zhao, Huihui Xie, Xue Han, Liming Lin, Yiting Lyu, Ke Xu, Jiajun Xu, Xiaowen Shi   +10 more
wiley   +1 more source

Detection of bovine herpesvirus type 1 and bovine ephemeral fever virus antigens in cattle lymph nodes using three immunological assays

Journal of Veterinary Medical Research, 2005
Lymph nodes (Ln) are the preferred samples for virus isolation and detection. In the present study, carcass and visceral Ln of apparently healthy cattle were screened for the presence of bovine herpes virus type 1 (BHV-1) and bovine ephemeral fever ...
S. M. Tamam, A. S. Abdel-Moneim
doaj  

Desenvolvimento e padronização do dot-Elisa para o diagnóstico sorológico da Maedi Visna

, 2007
A Maedi Visna é uma enfermidade típica de ovinos, embora possa infectar, também, caprinos. Encontra-se disseminada em todo mundo, exceto na Austrália e Nova Zelândia.
Aragão, Maria Alzira do Carmo
core  

Evaluation of new ‘indigenous milk dot-ELISA’ as ‘Field Test’ vis-à-vis milk plate-ELISA for the detection of Mycobacterium avium sub species paratuberculosis infection in lactating domestic livestock [PDF]

, 2016
166-171Mycobacterium avium subspecies paratuberculosis (MAP), the cause of incurable Johne’s disease (JD), is endemic in both domestic livestock and human population of the country.
Dhama, Kuldeep, Stephen, Bjorn John, Jayaraman, Sujata, Sahzad, Chaubey, Kundan Kumar, Chauhan, Jitendra, Sohal, Jagdip Singh, Gupta, Saurabh, Bhatia, Ashok Kumar, Pachoori, Anjali, Singh, Manju, Aseri, Gajendra Kumar, Singh, Shoor Vir   +12 more
core  

Macrophage RSAD2 Couples mtDNA Synthesis With a Self‐Amplifying Inflammatory Circuit to Orchestrate Tissue Repair

Advanced Science, EarlyView.
Macrophage RSAD2 dually regulates CMPK2—the rate‐limiting enzyme for mitochondrial DNA synthesis—by suppressing its ubiquitination and promoting its phosphorylation via Csnk2a2 recruitment. This amplifies mtDNA production, which simultaneously activates a cGAS‐STING‐IRF3‐RSAD2 feedforward loop and the NLRP3 inflammasome, driving a self‐sustaining ...
Haomiao Yuan, Shukui Du, Chunfei Li, Xinjie Li, Shuyang Mu, Anran Qu, Hengxu Yan, Chongchong Xu, Jinnong Yang, Jingkai Sun, Yijun Wang, Jiayang Xiao, Fuyuan Zhang, Linlin Wang, Tiegang Li, Rui Zhao, Dawei Guan   +16 more
wiley   +1 more source