Results 101 to 110 of about 4,903,274 (294)

Future measurements of the Lense-Thirring effect in the Double Pulsar

, 2016
The Double Pulsar system PSR J0737-3039A/B has proven to be an excellent laboratory for high precision tests of general relativity. With additional years of timing measurements and new telescopes like the Square Kilometre Array (SKA), the precision of ...
Kehl, Marcel S., Kramer, Michael, Liu, Kuo, Wex, Norbert   +3 more
core   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Comparing Gender Differences in Willingness to Accept Same- and Other-Sex Dyadic and Multi-Person Sexual Offers: An Examination of the Backlash Effect

Behavioral Sciences
Proponents of Sexual Script Theory posit that men and women differ in their sexual behaviors/motivations, often due to culturally ingrained expectations.
Ashley E. Thompson, Lizzy Bensen, Ryan Scoats   +2 more
doaj   +1 more source

Double-Effect Donation or Bodily Respect? A "Third Way" Response to Camosy and Vukov. [PDF]

Linacre Q, 2023
McCarthy A, Watt H.
europepmc   +1 more source

Coherent Electron-Phonon Coupling in Tailored Quantum Systems

, 2011
The coupling between a two-level system and its environment leads to decoherence. Within the context of coherent manipulation of electronic or quasiparticle states in nanostructures, it is crucial to understand the sources of decoherence.
A Pfund, A Stern, C Weber, CC Escott, EH Hwang, EM Weig, F Molitor, F Molitor, FA Zwanenburg, FHL Koppens, FT Vasko, H Bluhm, I Shorubalko, J Güttinger, JR Petta, KI Bolotin, R Hanson, R Leturcq, RG DeVoe, RH Dicke, S Nadj-Perge, S Schnez, T Brandes, T Choi, T Fujisawa, T Hayashi, TH Oosterkamp, U Gasser, WJM Naber   +28 more
core   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Effect of rosuvastatin on diabetic polyneuropathy: a randomized, double-blind, placebo-controlled Phase IIa study

Diabetes, Metabolic Syndrome and Obesity, 2014
Jaime Hernández-Ojeda, Luis Miguel Román-Pintos, Adolfo Daniel Rodríguez-Carrízalez, Rogelio Troyo-Sanromán, Ernesto Germán Cardona-Muñoz, María del Pilar Alatorre-Carranza, Alejandra Guillermina ...
Hernández-Ojeda J, Román-Pintos LM, Rodríguez-Carrízalez AD, Troyo-Sanromán R, Cardona-Muñoz EG, Alatorre-Carranza MP, Miranda-Díaz AG   +6 more
doaj  

Infecundity and the Principle of Double Effect in the Congregation for the Doctrine of the Faith's 2018 Responsum on Hysterectomy. [PDF]

Linacre Q, 2023
Dezort S.
europepmc   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Conformational analysis of 2,2-difluoroethylamine hydrochloride: double gauche effect

Beilstein Journal of Organic Chemistry, 2014
The gauche effect in fluorinated alkylammonium salts is well known and attributed either to an intramolecular hydrogen bond or to an electrostatic attraction between the positively charged nitrogen and the vicinal electronegative fluorine atom. This work
Josué M. Silla, Claudimar J. Duarte, Rodrigo A. Cormanich, Roberto Rittner, Matheus P. Freitas   +4 more
doaj   +1 more source