Results 91 to 100 of about 12,867,784 (306)

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Double-edged sword of artificial intelligence on energy consumption: Evidence from China

open access: yesChinese Journal of Population, Resources and Environment
: Energy consumption is tightly connected with resource depletion and environmental quality. As the core technology driving the contemporary sci-tech revolution and industrial transformation, artificial intelligence (AI) reshapes production processes and
Ruilin Hao, Wenjia Zhang, Shuxing Chen
doaj   +1 more source

Chinese Double Effect on Brazilian Foreign Policy (2003-2018) [PDF]

open access: yesContexto Internacional
This research examines contemporary Brazilian foreign policy, and its central concern is to explore how China’s global rise has impacted the general guidelines of Brazilian foreign policy from 2003 to 2018.
Yuri Bravo Coutinho   +1 more
doaj   +1 more source

Embryo loss and double effect [PDF]

open access: yesJournal of Medical Ethics, 2013
I defend the argument that if embryo loss in stem cell research is morally problematic, then embryo loss in in vivo conception is similarly morally problematic. According to a recent challenge to this argument, we can distinguish between in vivo embryo loss and the in vitro embryo loss of stem cell research by appealing to the doctrine of double effect.
openaire   +2 more sources

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Synthesis of shape-controlled particles based on synergistic effect of geometry confinement, double emulsion template, and polymerization quenching

open access: yes, 2012
We present a novel method to produce shape-controlled particles based on synergistic effect of geometry confinement, double emulsion template, and polymerization quenching. Based on the established method, a series of crescent and multi-pod particles can
Qin, Jianhua   +3 more
core   +1 more source

Consent and the Doctrine of Double Effect. [PDF]

open access: yes, 2022
The doctrine of double effect (DDE) explains that it may be permissible to cause harm as a foreseen side-effect of an action that brings about a good result but impermissible to cause harm as a means of bringing about the same good result. The DDE is commonly illustrated with the Trolley Problem, which along with similarly structured examples, have ...
Ocampo, Joshua, Phillips, Jonathan
openaire   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

Objective Double Effect and the Avoidance of Narcissism [PDF]

open access: yes, 2013
The Doctrine of Double Effect [DDE] states roughly that it is harder to justify causing or allowing harm as a means to an end than it is to justify conduct that results in harm as a side effect.
Nye, Howard
core   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

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