Results 51 to 60 of about 3,960,683 (297)
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Double Shear Testing of Cable Bolts with No Concrete Face Contacts [PDF]
, 2017 A new series of double shear tests were carried out using a newly modified double shear apparatus which prevented contacts between concrete block surfaces during shearing.
Li, Xuwei +13 more
core +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
RESEARCH for Face Detection on Improved Algorithm of AdaBoost
MATEC Web of Conferences, 2016 Face detection is basic research in computer visual field, it has important application value in the fields of cameras and surveillance and Automatic face recognition.
Chen Hong
doaj +1 more source
A criança e a prosódia: uma retrospectiva e novos desenvolvimentos
Cadernos de Estudos Lingüísticos, 2011 This is a retrospective of my former work on the acquisition of prosody and specifically the role of the double face of prosody in acquisition is revisited.
Ester Mirian Scarpa
doaj +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
The double face of the wind, like Jekyll and Hyde
Forest@, 2019 We talk shortly about negative and positive effects of the windstorm (Vaia) that swept the forests of the North-East in Italy last October. In addition to short-term economic and infrastructural damages, the most negative effect was on the local people ...
Borghetti M
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Double face sealing device [PDF]
, 1991 A double face sealing device for mounting between two surfaces to provide an airtight and fluid-tight seal between a closure member bearing one of the surfaces and a structure or housing bearing the other surface which extends around the opening or ...
Weddendorf, Bruce C.
core