Results 31 to 40 of about 1,483 (186)

A hitchhiker's guide to single‐cell epigenomics: Methods and applications for cancer research

open access: yesInternational Journal of Cancer, EarlyView.
Abstract Genetic mutations are well known to influence tumorigenesis, tumor progression, treatment response and relapse, but the role of epigenetic variation in cancer progression is still largely unexplored. The lack of epigenetic understanding in cancer evolution is in part due to the limited availability of methods to examine such a heterogeneous ...
Marta Moreno‐Gonzalez   +2 more
wiley   +1 more source

Key Considerations on CITE‐Seq for Single‐Cell Multiomics

open access: yesPROTEOMICS, EarlyView.
ABSTRACT CITE‐Seq (Cellular Indexing of Transcriptomes and Epitopes by Sequencing) is an advanced single‐cell sequencing method to profile both gene expression and protein abundance simultaneously in individual cells using single‐cell mRNA sequencing techniques alongside antibody‐derived tags (ADTs), for protein detection.
Hye‐Wong Song   +3 more
wiley   +1 more source

Laser Synthesis in Liquid Induced Lattice Distortion in PtFeSn/Activated Carbon for Enhanced Methylcyclohexane Dehydrogenation

open access: yesSmall Methods, EarlyView.
A Pt‐Fe‐Sn alloy catalyst supported on activated carbon is synthesized via laser synthesis in liquid, introducing lattice distortions that enhance active site exposure and toluene desorption. The catalyst achieves a hydrogen evolution rate of 2625 mmol gPt⁻¹ min⁻¹ with 99.96% selectivity and excellent stability, offering a promising strategy for ...
Zheng Wang   +5 more
wiley   +1 more source

Blockchain and Digital Technologies in the Telecommunications Industry

open access: yesThunderbird International Business Review, EarlyView.
ABSTRACT This article examines how fourth industrial revolution (4IR) technologies, specifically blockchain and digital twin technologies, can be utilized to address the energy supply challenge and enhance the management of distributed telecom infrastructure assets in a research context.
Charles Okeyia   +3 more
wiley   +1 more source

Tumour‐informed workflow to use ctDNA as a biomarker for risk of recurrence in head and neck cancer patients post‐treatment

open access: yesVIEW, EarlyView.
Our study presents a tumour‐informed circulating tumour DNA (ctDNA) workflow designed to enhance the detection of recurrence in head and neck cancer patients, addressing key challenges such as low ctDNA tumour fractions and tumour heterogeneity. Abstract Circulating tumour DNA (ctDNA) is a promising minimally invasive biomarker for monitoring treatment
Xiaomin Huang   +8 more
wiley   +1 more source

Blockchain technology disruptions: Exploring accounting and auditing academics and practitioners' perception

open access: yesAccounting &Finance, EarlyView.
Abstract This study explores the practical impact of blockchain technology (BCT), which contrasts strongly with literature that has predominantly hypothesised BCT's potential to disrupt accounting practice. We interviewed 44 practitioners and academics with knowledge of BCT across 13 countries and industries.
Musbaudeen Titilope Oladejo   +3 more
wiley   +1 more source

Single Cell Analysis Reveals Dynamic Changes of Distinct Cell Populations in Human Nickel Allergy

open access: yesAllergy, EarlyView.
We investigated cell types mediating the early and late inflammatory responses in human Ni2+‐allergy by scRNA‐Seq. Early responsiveness was mainly mediated by TLR4+TAGLN− endothelial cells indirectly activating TLR4−KRT16+ keratinocytes, and CCR7+DCN+ DCs. Late responsiveness was crucially driven by infiltration of KLF2+ central memory T cells and TLR4+
Marc Schmidt   +7 more
wiley   +1 more source

Prolonged IL‐33 Exposure Switches the Secreted Mast Cell Cytokine Profile From Pro‐Inflammatory to Pro‐Tolerant

open access: yesAllergy, EarlyView.
This study investigates the effect of IL‐33 and Hymenoptera venom on mast cell cytokine profiles under venom immunotherapy (VIT)‐like conditions. Our in vitro model of VIT‐like mast cell stimulation demonstrates a modulatory effect of IL‐33 on the secreted mast cell cytokine profile.
Andrea R. Teufelberger   +3 more
wiley   +1 more source

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