Results 71 to 80 of about 2,157,663 (242)

Mechanism‐Driven Screening of Membrane‐Targeting and Pore‐Forming Antimicrobial Peptides

open access: yesAdvanced Science, EarlyView.
To combat antibiotic resistance, this study employs mechanism‐driven screening with machine learning to identify pore‐forming antimicrobial peptides from amphibian and human metaproteomes. Seven peptides are validated, showing minimal toxicity and membrane disruption.
Jiaxuan Li   +9 more
wiley   +1 more source

Hashing based Answer Selection

open access: yes, 2019
Answer selection is an important subtask of question answering (QA), where deep models usually achieve better performance. Most deep models adopt question-answer interaction mechanisms, such as attention, to get vector representations for answers.
Li, Wu-Jun, Xu, Dong
core   +1 more source

Neuroprotective Effects of Time‐Restricted Feeding Combined With Different Protein Sources in MPTP‐Induced Parkinson's Disease Mice Model and Its Modulatory Impact on Gut Microbiota Metabolism

open access: yesAdvanced Science, EarlyView.
Time‐restricted feeding (TRF) exerts protein‐dependent neuroprotective effects in an MPTP‐induced Parkinson's disease model. In casein‐fed mice, TRF improves gut barrier integrity and reduces neuroinflammation, possibly via modulation of Allobaculum and BCAAs.
Ting Li   +12 more
wiley   +1 more source

Dorsal Raphe VIP Neurons Are Critical for Survival‐Oriented Vigilance

open access: yesAdvanced Science, EarlyView.
DRNVIP neurons in mice and primates are strategically positioned to influence the central extended amygdala via feedback loops. They regulate the excitability of PKC‐δ neurons in the ovBNST and CeA through glutamate release. Their ablation heightens activity in these regions, disrupts active‐phase sleep architecture, enhances risk assessment behaviors ...
Adriane Guillaumin   +15 more
wiley   +1 more source

Distributed Ledger Technology for IoT: Parasite Chain Attacks

open access: yes, 2020
Directed Acyclic Graph (DAG) based Distributed Ledgers can be useful in a number of applications in the IoT domain. A distributed ledger should serve as an immutable and irreversible record of transactions, however, a DAG structure is a more complicated ...
Cullen, Andrew   +3 more
core   +1 more source

Performance Investigation of Eco‐Friendly Refrigerant Mixtures as an Alternative to R134a in Vapour‐Compression Refrigeration System

open access: yesAsia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT The growing impacts of climate change and energy scarcity demand environmentally sustainable refrigeration solutions. This study investigates eco‐friendly refrigerants (R152a, R290 and R600a) and their optimized ternary mixture as alternatives to R134a. Four blend compositions were analysed using experimental testing and REFPROP 10.0 modelling
M. Periyasamy, P. Senthilkumar
wiley   +1 more source

Confirmation of a Non‐Transiting Planet in the Habitable Zone of the Nearby M Dwarf L 98‐59

open access: yesAstronomische Nachrichten, EarlyView.
ABSTRACT Only 40 exoplanetary systems with five or more planets are currently known. These systems are crucial for our understanding of planet formation and planet‐planet interaction. The M dwarf L 98‐59 has previously been found to show evidence of five planets, three of which are transiting.
Paul I. Schwarz   +2 more
wiley   +1 more source

Hyperledger Fabric for the (digitalized) lifecycle of construction products: Applied review on fastening technology

open access: yesCivil Engineering Design, Volume 7, Issue 1, Page 9-22, March 2025.
Abstract Blockchain technology is a digital decentralized data ledger recording transactions in an encrypted format. Its implementation can potentially hold significant advantages for the built environment, particularly in manufacturing and building product usage aligned with Building Information Modeling (BIM). This paradigm shift toward decentralized
Aileen Pfeil   +2 more
wiley   +1 more source

Exploring Differences Between Similarly Structured State Higher Education Governing Agencies

open access: yesNew Directions for Higher Education, EarlyView.
ABSTRACT Research examining state higher education governing agencies often focuses on their centralization of authority and structure as key differentiating factors (e.g., consolidated governing agencies vs. coordinating boards vs. planning/regulatory agencies).
Paul G. Rubin, Lucas N. English
wiley   +1 more source

Hashing for Similarity Search: A Survey [PDF]

open access: yes, 2014
Similarity search (nearest neighbor search) is a problem of pursuing the data items whose distances to a query item are the smallest from a large database.
Ji, Jianqiu   +3 more
core  

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