Results 31 to 40 of about 27,026 (255)

Caractérisation expérimentale de plasmas induits par impulsion laser en régime de double impulsion

Journal International de Technologie, de l'Innovation, de la Physique, de l'Energie et de l'Environnement, 2019
La spectroscopie optique d’émission sur plasma induit par laser (LIBS, acronyme de Laser-Induced Breakdown Spectroscopy) est aujourd’hui une puissante méthode d’analyse de composition multi-élémentaire. Ce procédé utilisant  une source laser impulsionnelle permet en effet de déterminer une quantité importante d’informations  relatives au plasma généré ...
Favre, Aurélien, Morel, Vincent, Grisolia, C., Bultel, Arnaud   +3 more
openaire   +3 more sources

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Closed-form overturning limit of rigid block under critical near-fault ground motions

Frontiers in Built Environment, 2016
A closed-form limit on the input level of the double impulse as a substitute of a near-fault ground motion is derived for the overturning of a rigid block.
Kunihiko eNabeshima, Ryo eTaniguchi, Kotaro eKojima, Izuru eTakewaki   +3 more
doaj   +1 more source

Impulsive Synchronization Between Double-Scroll Circuits

, 2012
Two identical, double-scroll circuits, in their chaotic mode of operation, are unidirectionally connected via an externally triggered electronic switch. Thus, the case of impulsive synchronization is established. Their synchronization and its dependence on the switch on-off frequency and duty cycle is demonstrated.
Volos, Ch. K., Stavrinides, S. G., Kyprianidis, I. M., Stouboulos, I. N., Özer, Mehmet, Anagnostopoulos, A. N.   +5 more
openaire   +2 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Experimental investigation of cavity dynamics and pressure created by cumulative hydrodynamic ram

Results in Engineering, 2021
The impact of high-velocity projectile on fluid-filled containers can cause hydrodynamic ram (HRAM) events. When multiple projectiles impact, HRAM effect is superimposed.
Yangziyi Ji, Xiangdong Li, Lanwei Zhou, Anran Chen   +3 more
doaj   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Interface Adhesion Property and Laser Ablation Performance of GAP-PET Double-Layer Tape with Plasma Treatment

Nanomaterials, 2022
In the field of laser ablation micro-propulsion, the property of double-layer tape has significant impact on the propulsion performance. In this paper, low temperature plasma was used to treat the surface of polyethylene terephthalate (PET) to improve ...
Sibo Wang, Bangdeng Du, Baoyu Xing, Yanji Hong, Ying Wang, Baosheng Du, Yongzan Zheng, Jifei Ye, Chenglin Li   +8 more
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source