Results 41 to 50 of about 1,649,082 (293)
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw +5 more
wiley +1 more source
Experimental investigation of cavity dynamics and pressure created by cumulative hydrodynamic ram
Results in Engineering, 2021 The impact of high-velocity projectile on fluid-filled containers can cause hydrodynamic ram (HRAM) events. When multiple projectiles impact, HRAM effect is superimposed.
Yangziyi Ji +3 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Introduction/Objective Acute intracranial stenting during endovascular thrombectomy (EVT) for ischemic stroke requires intraprocedural antiplatelet therapy (APT) to maintain patency. However, the hemorrhagic risk of combining APT with intravenous thrombolysis (IVT) remains uncertain.
Aaron Rodriguez‐Calienes +75 more
wiley +1 more source
Digital Cognitive Phenotyping for Differential Diagnosis and Monitoring in Neurological Conditions
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To assess the utility, accessibility, and equivalence to supervised scales of online cognitive assessment in older individuals with cognitive impairment. Methods Patients with Alzheimer's disease (AD, n = 31), idiopathic normal pressure hydrocephalus (iNPH, n = 26), and traumatic brain injury (TBI, n = 23) completed online cognitive ...
Martina Del Giovane +10 more
wiley +1 more source
, 2022 1. Intallation body; 2. Impulse bag filter; 3.Cyclone separator; 4. Cyclone dryer; 5. Impulse dryer; 6. Helical feeder; 7. Air inlet pipe; 8. Air filter; 9. Air regulating valve; 10. Fan; 11. Feed port; 12. Air inlet port; 13. Exhaust port; 14.
Feng Chen (25347) +2 more
core +1 more source
Impulse ageing of polymeric materials
, 2011 Impulse over-voltage is a common phenomenon in electric power systems. A switching impulse is created by a switching surge or local fault while a lightning impulse is due to direct lightning strike to high voltage plant such as an overhead line.
Dao, Ngoc Long
core +1 more source
Tower Air-gaps discharge characteristics and insulation coordination for UHV AC double-circuit line
The Journal of Engineering, 2019 In order to give out inverse V-type insulator tower air-gaps configuration of double-circuit UHV AC power transmission line, different distance air-gaps from high-voltage electrode to tower frame discharge tests of inverse V-string are carried out ...
Huo Feng, Nan Jing, Ye Qiming, Ma Yeming
doaj +1 more source
Double Perturbations for Impulsive Differential Equations in Banach Spaces
Taiwanese Journal of Mathematics, 2016 In this article, we are concerned with the existence of extremal solutions to the initial value problem of impulsive differential equations in ordered Banach spaces. The existence and uniqueness theorem for the solution of the associated linear impulsive differential equation is established.
Chen, Pengyu +2 more
openaire +2 more sources
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem +9 more
wiley +1 more source
Characterization in stand-up comedy: From Ted Ray to Billy Connolly, via Bertolt Brecht [PDF]
, 2000 Stand-up comedy is often distinguished from straight acting by its apparent lack of characterization-the comedian appearing onstage apparently as him or herself.
Double, Oliver
core +1 more source