Results 131 to 140 of about 10,952,065 (350)

Library As Place: Being Human in a Digital World

open access: yes, 2014
Despite the increasingly digital nature of information retrieval, both users and computers continue to occupy physical space, and the library – as place – offers an essential location for inspiration.
Clark, Amanda C.R.
core   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

Property and the Construction of the Information Economy: A Neo-Polanyian Ontology [PDF]

open access: yes, 2018
This chapter considers the changing roles and forms of information property within the political economy of informational capitalism. I begin with an overview of the principal methods used in law and in media and communications studies, respectively, to ...
Cohen, Julie E.
core   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

Disasters and Disclosures [PDF]

open access: yes, 2018
Many securities fraud lawsuits follow corporate disasters of some sort or another, claiming that known risks were concealed prior to the crisis. Yet for a host of doctrinal, pragmatic and political reasons, there is no clear-cut duty to disclose these ...
Langevoort, Donald C
core   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

open access: yesMolecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir   +2 more
wiley   +1 more source

Materiality, Parthood, and Possibility [PDF]

open access: yes
This paper offers an argument in favour of a Lewisian version of concretism that maintains both the principle of material inheritance (according to which, if all the parts of an object x are material, then x is material) and the materiality-modality link
Iaquinto, Samuele, Torrengo, Giuliano
core  

No TV for Woodpeckers by Gary Barwin, If Pressed by Andrew McEwan, and Ecology without Culture: Aesthetics for a Toxic World by Christine L. Marran [PDF]

open access: yes, 2018
Review of Gary Barwin\u27s No TV for Woodpeckers, Andrew McEwan\u27s If Pressed, and Christine L.
Sloane, Michael D
core   +1 more source

Dumping Dredged Material with Double-Tremie

open access: yesPROCEEDINGS OF CIVIL ENGINEERING IN THE OCEAN, 1997
Double-tremie work was applied to mitigate some effects caused by dumping dredged materials. Field investigations were carried out in order to clarify its efficiency, which can reduce the discharge of suspended solids by circulating water body in it.
Kenichi Okumura   +5 more
openaire   +2 more sources

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

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