Results 61 to 70 of about 1,857 (290)
While the development of globally accepted sustainability reporting standards initiated by the IFRS Foundation has largely engaged stakeholders in developed economies, the stakes for developing economies could be compromised without an explicit ...
Artie W. Ng +2 more
core +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Reporting in circles? How public firms navigate ESRS E5 on the circular economy [PDF]
In 2024, the first annual reports prepared under the CSRD guidelines were published. This study examines how 75 companies listed on the Amsterdam stock exchange report on their performance regarding the circular economy, as framed in ESRS E5, with the ...
Karen Maas +2 more
doaj +3 more sources
The concept of double materiality is developing rapidly, with potential implications for monetary and financial policies. Double materiality builds on the historical accounting and auditing convention of materiality and expands it by considering that non-
Salin, Mathilde +4 more
core
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Evaluating double materiality reporting in 2022 /Italy: insights from 2022 annual reports of Italian listed companies [PDF]
This study delves into the application and challenges of double materiality in non financial reporting among Italian companies listed on the FTSE MIB Index, in response to the European Directive 2022/2464 (CSRD).
Croxatto, Simone
core
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
The Evolution of Environmental Accounting and Assurance Practices: A Systematic Review of Standards, Methods, and Policy Integration [PDF]
The increasing focus on sustainability and climate responsibility is driving the development of environmental accounting and assurance practices as instruments of transparency and accountability.
Kusumaningsih Ambar +6 more
doaj +1 more source

