Results 61 to 70 of about 252 (209)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Contents [PDF]

Zeszyty Teoretyczne Rachunkowości
Contents / Spis treściJoanna Krasodomska, Nadia Albu, Anna Szychta, Editorial – Od Zespołu Redakcyjnego 7Mohamed Anas Belidan, Halima Baghad, Navigating materiality in sustainability reporting: A scoping review of single and double materiality approaches–
doaj   +1 more source

Reporting in circles? How public firms navigate ESRS E5 on the circular economy [PDF]

MAB
In 2024, the first annual reports prepared under the CSRD guidelines were published. This study examines how 75 companies listed on the Amsterdam stock exchange report on their performance regarding the circular economy, as framed in ESRS E5, with the ...
Karen Maas, Diane Zandee, Marleen Janssen Groesbeek   +2 more
doaj   +3 more sources

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Regulatory Alignment of Selected Colombian Sustainability Disclosure Instruments with ISSB, ESRS and GRI Standards: A Comparative Analysis

Journal of Sustainability
This study evaluates the degree of regulatory alignment between selected Colombian sustainability disclosure instruments and leading international sustainability reporting frameworks, particularly the International Sustainability Standards Board ...
Katya Margarita Mendez-Maldonado, Flor Nancy Díaz-Piraquive, Leonardo Daniel Amell Arinez, Flor Estela Quiroga Mora   +3 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Sustainability reporting and assurance practices in agribusiness: a comparative institutional analysis of Ukraine and Germany

Agricultural and Resource Economics
Purpose. The aim of the study is to assess the institutionalisation of sustainability reporting and assurance practices in the agricultural sectors of Ukraine and Germany through the conceptual lenses of legitimacy, institutionalisation, and political ...
Volodymyr Metelytsia, Volodymyr Kraievskyi, Serhii Taran   +2 more
doaj   +1 more source

The Evolution of Environmental Accounting and Assurance Practices: A Systematic Review of Standards, Methods, and Policy Integration [PDF]

E3S Web of Conferences
The increasing focus on sustainability and climate responsibility is driving the development of environmental accounting and assurance practices as instruments of transparency and accountability.
Kusumaningsih Ambar, Pratiwi Vivi, Putikadea Insyirah, Nilasari Aprillia, Farida Panduwinata Lifa, Adimas Ganda Saputra Irwan, Hazrol Yusoff Yusri   +6 more
doaj   +1 more source