Results 71 to 80 of about 1,857 (290)
Double materiality -from theory to practice, an examination of its early implementation
International audienceThe term "Double Materiality" (DM) was first used by the European Commission (EC) in the 2019 "Guidelines on Non-Financial Reporting: Supplement on Reporting Climate-Related Information" (2019/C 209/01).
Shami, Anis
core
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Contents / Spis treściJoanna Krasodomska, Nadia Albu, Anna Szychta, Editorial – Od Zespołu Redakcyjnego 7Mohamed Anas Belidan, Halima Baghad, Navigating materiality in sustainability reporting: A scoping review of single and double materiality approaches–
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
The Corporate Sustainability Reporting Directive (CSRD) marks a major shift in EU sustainability reporting by requiring compliance with the European Sustainability Reporting Standards (ESRS). This study examines how a sample of Norwegian companies relate
Jørgen Kjøsen Lindgren +3 more
doaj +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
The wood: Cover of the art and metaphor of the return from 1968
The landscape genre resurfaced with renewed forces beginning in the sixties of the twentieth century through the land art and the earthworks. The pioneers Americans felt a special love for the desert and the places which are difficult to access by ...
Ana Esther Santamaría Fernández
doaj +1 more source
The Backward in Time Problem of Double Porosity Material with Microtemperature [PDF]
In the present study, the theory of thermoelastodynamics is considered in the case of materials with double porosity structure and microtemperature. The novelty of this study consists in the investigation of a backward in time problem associated with double porous thermoelastic materials with microtemperature. In the first part of the paper, in case of
openaire +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source

