Results 101 to 110 of about 3,402 (282)

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

DOUBLE NEGATION IN ROMANIAN AND ENGLISH LANGUAGES

open access: yesStudia Universitatis Moldaviae: Stiinte Umanistice, 2007
Dubla negaţie apare atunci când două forme ale negaţiei se folosesc în aceeaşi propoziţie. În unele limbi, utilizarea dublei negaţii într-o propoziţie rezultă într-un enunţ cu sens negativ, în timp ce în alte limbi – într-un enunţ cu sens pozitiv, atât ...
USM ADMIN
doaj  

Under the Gaze of Double Critique: De-colonisation, De-sacralisation and the Orphan Book

open access: yesTidsskrift for Islamforskning, 2017
Instead of the orientalist reformist paradigm as frame and episteme, Khatibi proposes a theory of double critique, critical liminality that targets, in a bi-directional movement, a Eurocentric or Orientalist discourse and an ethnocentric local discourse.
Joshua A. Sabih
doaj   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Double negation of the nene- type (nenedostal, nenepatrný) in Czech [PDF]

open access: yes
This bachelor thesis examines double negation in Czech expressed by repeating the negative particle ne- twice in immediate succession. For the research, we aimed to find as many examples of words with this type of double negation as possible, gathering ...
Hartmanová, Lucie
core   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Negative constructions in selected Middle English verse texts

open access: yes, 2012
The objective of the present study is to investigate the historical development of negative constructions in ME verse and to provide a descriptive account of it. The central issues analyzed in this thesis are: (1) the usage of the negative adverbs 'ne'
Iyeiri, Yoko
core  

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

Double negation and information structure: somewhere between topic and focus

open access: yes, 2006
This paper examines the properties of double negation. Starting form the observation that despite the differences in the syntactic realisation of negation, languages such as Hungarian, French and English resort to the same strategies for marking double ...
Puskas, Genoveva
core  

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