Results 81 to 90 of about 3,402 (282)

Negation in vernacular Brazilian Portuguese

open access: yes, 2013
textAs Haegeman and Zanuttini (1996:117) discuss, when two negative elements are present in a specific syntactic domain, two possible situations may arise: "(i) the two negative elements may cancel each other out, or (ii) the two elements may ...
Martínez, Cristina, active 2003
core  

Residuated Structures Derived from Commutative Idempotent Semirings

open access: yesDiscussiones Mathematicae - General Algebra and Applications, 2019
Since the reduct of every residuated lattice is a semiring, we can ask under what condition a semiring can be converted into a residuated lattice. It turns out that this is possible if the semiring in question is commutative, idempotent, G-simple and ...
Chajda Ivan, Länger Helmut
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Classical polarizations yield double-negation translations [PDF]

open access: yes, 2016
Double-negation translations map formulas to formulas in such a way that if a formula is a classical theorem then its translation is an intuitionistic theorem.
Chihani, Zakaria   +2 more
core  

Double negation stable h-propositions in cubical sets

open access: yes, 2022
We give a construction of classifiers for double negation stable h-propositions in a variety of cubical set models of homotopy type theory and cubical type theory.
Swan, Andrew W.
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Preverbal negative markers in Buli

open access: yes, 2009
This article deals with some aspects of negation in Buli, a Gur language spoken by the Bulsa people in Northern ...
Schwarz, Anne
core  

Croatian secondary school students’ errors in forming syntactic negation in English [PDF]

open access: yesHum, 2019
The acquisition of negation in the second language has been investigated in numerous studies (Cancino et al., 1975; Meisel, 1997;Fuentes, 2008), however, there are no systematic studies of the acquisition of the English negation by speakers of the ...
Iva Grubišić Ćurić
doaj  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

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