Results 91 to 100 of about 3,402 (282)

Delimited control operators prove Double-negation Shift

open access: yes, 2012
International audienceWe propose an extension of minimal intuitionistic predicate logic, based on delimited control operators, that can derive the predicate-logic version of the Double-negation Shift schema, while preserving the disjunction and existence
Ilik, Danko
core   +1 more source

Doubly–Negating Complicatedness of Undoing Love: A Stylistic Reading of I Can’t Unlove You by Kenny Rogers

open access: yesHumaniora, 2013
This wasa research about the role of linguistic features in contributing to the overall meaning of a song entitled I Can’t Unlove You by Kenny Rogers.
Akun Akun
doaj   +3 more sources

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Double-Negation Elimination in Some Propositional Logics

open access: yes, 2002
This article answers two questions (posed in the literature), each concerning the guaranteed existence of proofs free of double negation. A proof is free of double negation if none of its deduced steps contains a term of the form n(n(t)) for some term t,
Larry Wos, Robert Veroff, Michael Beeson
core  

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

L’horizon de la logique lemmique

open access: yesEbisu: Études Japonaises, 2013
Yamanouchi Tokuryū, developing the thought expressed by Nāgārjuna in his Fundamental Verses of the Middle Way, formalized a logic of the lemma differing from that of the logos, viz. the tetralemma combining the four lemmas: 1. A; 2. Ā (non-A); 3. neither
Nobuo Kioka
doaj   +1 more source

Modalities Based on Double Negation

open access: yes, 2019
Modal operators play an important role in fuzzy theory, and in recent years researchers have devoted more effort on this topic. Here we concentrate on continuous strictly monotonously increasing Archimedian t-norms. In our study, we will construct modal operators related to negation operators and we introduce graded modal operators.
openaire   +2 more sources

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

The Revolution of The Transcendence

open access: yesKanz Philosophia: A Journal for Islamic Philosophy and Mysticism, 2011
Contrary to the general and common idea that Islam etymologically means submission, surrendering, servitude or even slavery, this paper tries to prove just the opposite, that Islam is a protest, an opposition and a revolution.
Hassan Hanafi
doaj   +1 more source

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