Results 61 to 70 of about 1,100,143 (252)
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Double Reduction Policy in Chinese Education: Promises, Outcomes, Perspectives
Вопросы образованияThe educational system of China has traditionally been heavily focused on exams, placing a significant academic burden on students and financial pressure on their parents, while also increasing teachers’ workload. The goal of the Double Reduction Policy (
Irina Shcheglova +6 more
doaj +1 more source
Symmetries, Associated First Integrals, and Double Reduction of Difference Equations
Abstract and Applied Analysis, 2014 We determine the symmetry generators of some ordinary difference equations and proceeded to find the first integral and reduce the order of the difference equations.
L. Ndlovu +3 more
doaj +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Speed reduction in aviation: A double dividend for decarbonization
Transportation Research Interdisciplinary PerspectivesAviation faces a structural paradox: five decades of efficiency gains have been absorbed by traffic growth, and absolute emissions continue to rise. Existing sector-wide decarbonization scenarios from ICAO and IATA rest almost entirely on Sustainable ...
Jean-Baptiste Jarin
doaj +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Comment on three papers about Hardy–Weinberg equilibrium tests in autopolyploids
Frontiers in Genetics, 2022 David Gerard
doaj +1 more source
Study on vibro-acoustic transmission characteristics of ship's double-layer acoustic bridge
Zhongguo Jianchuan YanjiuObjectivesThe inter-ship structure between double-layer shells is an important bridge for the transmission of acoustic vibration from pressure shell to light shell.
Zihao LIU +4 more
doaj +1 more source